DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and angptl6

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001014821.1	Gene:	angptl6 / 561927	ZFINID:	ZDB-GENE-030131-9735	Length:	489	Species:	Danio rerio

Alignment Length:	211	Identity:	80/211 - (37%)
Similarity:	120/211 - (56%)	Gaps:	8/211 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ELNPKKSGVQKIQVGSD--VIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNF 103
            |...|.||:..::..:.  :::.:||.:.|..||.|:|||.....||:|.|..|:.|||:|.|.:
Zfish   284 ESGEKTSGIYLLRPRNTNRLLQAWCDQSRAQGGWTVIQRRQDGSVNFFRTWDQYKQGFGNLDGEY 348

  Fly   104 FIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYH 168
            ::||.:|..::|....:|.:.:.|:.|.:.||.|..|.| ...|::...:||:|.||||||||:|
Zfish   349 WLGLEHLYWLTSQATYKLRVAMEDWQGRQVYAEYDSFRV-EPESDWYRLRLGSYQGTAGDSLSWH 412

  Fly   169 LYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEW 233
            ..:.|:|.|||.|..|.|||....|.|||..|..    |||||.:..|.|. .:.:..|:.|.|:
Zfish   413 NNKAFTTLDRDKDAYTGNCAHYQKGGWWYHMCAH----SNLNGVWYRGGHY-RSRYQDGVYWAEF 472

  Fly   234 KGFTYSYKTVNIMVRP 249
            .|.:||.|.|.:|::|
Zfish   473 HGGSYSLKKVAMMIKP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	80/211 (38%)
angptl6	NP_001014821.1	DUF1640	<46..150	CDD:285090
		DUF4349	<126..230	CDD:305044
		FReD	274..488	CDD:238040	79/209 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4088
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	1	1.000	-	-		mtm6515
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.860