DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5550 and angptl4

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001243132.1	Gene:	angptl4 / 492647	ZFINID:	ZDB-GENE-041111-222	Length:	460	Species:	Danio rerio

Alignment Length:	225	Identity:	79/225 - (35%)
Similarity:	110/225 - (48%)	Gaps:	21/225 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SSSCKEL---NPKKSGVQKIQVG-SDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGF 96
            :|.|.||   ....||:..||.. |...||||::|..| ||.|:|||.....:|.:.|.:||.||
Zfish   239 ASDCHELFLRGETSSGLYTIQPSDSQPFEVYCEMTPEG-GWTVIQRRQDGSVDFDQLWQAYQNGF 302

  Fly    97 GDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTA 161
            |:|.|.|::||..::.:|......|.::..|:..|.:...|. ||:....:||.:..|.:.:|..
Zfish   303 GNLNGEFWLGLEKIHSVSKGGNYILKVQFSDWRDEIQSISYR-FHLNGQENNYSLRILESPAGNT 366

  Fly   162 GDSLSYHLYQ-PFSTFDRDNDNAT-INCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPA-- 222
            ..||...... ||||.|:|||... :|||.:..|.||:..| .|   |||||.|.    ..||
Zfish   367 ESSLPTETSAVPFSTRDKDNDQKNDLNCAKQLSGGWWFSNC-GR---SNLNGRYF----VTPAPK 423

  Fly   223 ---LFGSGIVWGEWKGFTYSYKTVNIMVRP 249
               ....|:.|..|:|..|..||..:|:.|
Zfish   424 QRHQRKQGVFWKTWRGRYYPLKTTTMMIAP 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	79/225 (35%)
angptl4	NP_001243132.1	DUF4795	78..>224	CDD:292662
angptl4	NP_001243132.1	FReD	240..453	CDD:238040	78/222 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900