DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Fga

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001008724.1	Gene:	Fga / 361969	RGDID:	2603	Length:	782	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	90/262 - (34%)
Similarity:	130/262 - (49%)	Gaps:	38/262 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ASAEIGENVKIQTYKKYSS----SCKE-LNPKKSGVQ------KIQVGSDVIEVYCDVTIAGKGW 72
            |::|..:....:|.|:..:    .|.: |....||.|      |:...|.:..||||...:..||
  Rat   524 AASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGAQNGIFSIKLPGSSKIFSVYCDQETSLGGW 588

  Fly    73 LVVQRRVSVEENFYRNWTSYQTGFGDL----KGNFFIGLNNLNKISSLQPQELYIELVDFAGEKR 133
            |::|:|:....||.|.|..|:.|||.|    :|.|::| |:...:.:|:...|.:||.|:||::.
  Rat   589 LLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLG-NDYLHLLTLRGSVLRVELEDWAGKEA 652

  Fly   134 YAHYSVFHVGNVYSNYPITQLGAYSGTAGDSL-----------SYHLYQPFSTFDRDNDNATINC 187
            ||.|. |.||:....|.: |:.:|.|||||:|           :.|....|||||||.|....||
  Rat   653 YAEYH-FRVGSEAEGYAL-QVSSYQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEENC 715

  Fly   188 AARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPA-----LFGSGIVWGEWKGFTYSYKTVNIMV 247
            |..|.|.|||..|    ..:||||.|..|...||.     ...:|:||..::|..||.:.|.:.:
  Rat   716 AEVYGGGWWYNSC----QAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKI 776

  Fly   248 RP 249
            ||
  Rat   777 RP 778

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	86/247 (35%)
Fga	NP_001008724.1	Fib_alpha	51..189	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..374
		Fibrinogen_aC	388..453	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	522..542		4/17 (24%)
		FReD	546..779	CDD:238040	86/240 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810