DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and tnn

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_005171321.1	Gene:	tnn / 30234	ZFINID:	ZDB-GENE-990415-262	Length:	1020	Species:	Danio rerio

Alignment Length:	262	Identity:	83/262 - (31%)
Similarity:	129/262 - (49%)	Gaps:	40/262 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FYLASAEIGEN--VKIQTYK-------------------KYSSSCKEL---NPKKSGVQKIQVG- 55
            |.|:..|:|:.  |.:..|:                   ::...|.::   ...:|||..|.|.
Zfish   753 FALSGLEMGKKYIVTLIAYRGSKRSKIVETTFSTVGLAYQFPMDCTQIMRNGNMESGVYTIYVNN 817

  Fly    56 --SDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQP 118
              |..::||||:...|.||:|.|||.:.:.:|.:.|..|..|||:|...|::||:.::::::...
Zfish   818 NRSRTMQVYCDMKTDGGGWIVFQRRNTGKVDFMKKWRDYMKGFGELTEEFWLGLDKIHELTNTPT 882

  Fly   119 Q-ELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDN 182
            | |...:| ....:::||.|..|.|......:.:| :|:|.|.|||:::||...||||.|.|||.
Zfish   883 QYEARFDL-GSGSDRKYAVYDNFKVAPSKQKFKLT-IGSYKGNAGDAMTYHQGAPFSTVDSDNDI 945

  Fly   183 ATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMV 247
            |..|||..:.|||||:.|    ..:||||.:....|:      .|:.|..|||...|.....|.:
Zfish   946 ALGNCALTHQGAWWYKNC----HLANLNGRFGDNRHS------MGVNWEPWKGHLQSLDFAEIKI 1000

  Fly   248 RP 249
            ||
Zfish  1001 RP 1002

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	77/223 (35%)
tnn	XP_005171321.1	EGF_alliinase	<133..163	CDD:282688
		EGF_2	161..189	CDD:285248
		EGF_2	193..220	CDD:285248
		EGF_2	224..251	CDD:285248
		fn3	257..333	CDD:278470
		fn3	344..426	CDD:278470
		fn3	435..514	CDD:278470
		fn3	523..602	CDD:278470
		fn3	611..683	CDD:278470
		fn3	699..773	CDD:278470	6/19 (32%)
		FReD	792..1003	CDD:238040	77/223 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3724
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810