DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Angptl6

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001100172.1	Gene:	Angptl6 / 298698	RGDID:	1311141	Length:	457	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	78/203 - (38%)
Similarity:	116/203 - (57%)	Gaps:	6/203 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KSGVQKIQVGSDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNL 110
            :|||.::::|..|:.|:|:....|.||.|:|||.....||:.||..|:.|||...|.:::||..:
  Rat   257 QSGVYELRLGRRVVPVWCEQQQEGGGWTVIQRRQDGSVNFFTNWQHYKVGFGRPDGEYWLGLEPV 321

  Fly   111 NKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQPFST 175
            ::::|....||.|.|.|:.|....|||..|.:.....:|.: :||.|.|.||||||:|..:||:|
  Rat   322 HQVTSRGDHELLILLKDWGGRGARAHYDSFSLEPESDHYRL-RLGQYHGDAGDSLSWHSDKPFNT 385

  Fly   176 FDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSY 240
            .|||.|:.:.|||..:.|.|||..|..    |||||.:..|.|. .:.:..|:.|.|::|..||.
  Rat   386 VDRDRDSYSGNCALYHRGGWWYHACAH----SNLNGVWYHGGHY-RSRYQDGVYWAEFRGGAYSL 445

  Fly   241 KTVNIMVR 248
            |...::.|
  Rat   446 KKAAMLTR 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	78/203 (38%)
Angptl6	NP_001100172.1	Uso1_p115_C	66..>157	CDD:282695
Angptl6	NP_001100172.1	FReD	242..453	CDD:238040	77/201 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810