DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5550 and ANGPT1

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001137.2	Gene:	ANGPT1 / 284	HGNCID:	484	Length:	498	Species:	Homo sapiens

Alignment Length:	211	Identity:	77/211 - (36%)
Similarity:	114/211 - (54%)	Gaps:	18/211 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 KSGVQKIQVGS--DVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLN 108
            |||:..|.:.:  :..:|:|::.:.|.||.|:|.|.....:|.|.|..|:.|||:..|.:::|..
Human   296 KSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNE 360

  Fly   109 NLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLY-QP 172
            .:..|:|.:...|.|||:|:.|.:.|:.|..||:||...||.: .|..::||||...|..|: ..
Human   361 FIFAITSQRQYMLRIELMDWEGNRAYSQYDRFHIGNEKQNYRL-YLKGHTGTAGKQSSLILHGAD 424

  Fly   173 FSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAY--LGGNHTDPALFG--SGIVWGEW 233
            |||.|.||||....||....|.||:..|    ..|||||.:  .|.||      |  :||.|..:
Human   425 FSTKDADNDNCMCKCALMLTGGWWFDAC----GPSNLNGMFYTAGQNH------GKLNGIKWHYF 479

  Fly   234 KGFTYSYKTVNIMVRP 249
            ||.:||.::..:|:||
Human   480 KGPSYSLRSTTMMIRP 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	77/211 (36%)
ANGPT1	NP_001137.2	Smc	<81..280	CDD:224117
ANGPT1	NP_001137.2	FReD	281..496	CDD:238040	77/211 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41874
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810