DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Tnr

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_037177.2	Gene:	Tnr / 25567	RGDID:	3886	Length:	1358	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	87/206 - (42%)
Similarity:	126/206 - (61%)	Gaps:	15/206 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SGVQKIQVGSDV---IEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLN 108
            |||..|.:..::   ::||||:|..|.||:|.|||.:.:.:|:|.|..|:.|||:|:..|::||:
  Rat  1149 SGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLD 1213

  Fly   109 NLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQPF 173
            |:::|::....||.:::.| ..|..:|:|..|.|.:..|.|.: ::|.|:||||||||||..:||
  Rat  1214 NIHRITAQGRYELRVDMRD-GQEAVFAYYDKFAVEDSRSLYKL-RIGGYNGTAGDSLSYHQGRPF 1276

  Fly   174 STFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTY 238
            ||.|||||.|..|||..|.|||||:.|..    :||||.|....|:      .||.|..|||..:
  Rat  1277 STEDRDNDVAVTNCAMSYKGAWWYKNCHR----TNLNGKYGESRHS------QGINWYHWKGHEF 1331

  Fly   239 SYKTVNIMVRP 249
            |...|.:.:||
  Rat  1332 SIPFVEMKMRP 1342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	87/206 (42%)
Tnr	NP_037177.2	exchanger_TraA	<190..>328	CDD:411343
		EGF_Tenascin	203..231	CDD:376143
		fn3	328..398	CDD:394996
		fn3	416..496	CDD:394996
		fn3	507..586	CDD:394996
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:394996
		fn3	776..855	CDD:394996
		fn3	865..944	CDD:394996
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020
		FReD	1134..1342	CDD:238040	85/204 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I3664
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19143
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910