Protein Alignment CG5550 and ANGPTL2

DIOPT Version :9

• Sequence 1: NP_001246376.1
• Gene: CG5550 / 36883
• FlyBaseID: FBgn0034160
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_036230.1
• Gene: ANGPTL2 / 23452
• HGNCID: 490
• Length: 493
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 80/228 - (35%)
• Similarity: 126/228 - (55%)
• Gaps: 20/228 - (8%)

  Fly    36 SSSCKELNPKKSGVQKIQVGSD--------------VIEVYCDVTIAGKGWLVVQRRVSVEENFY 86
            ||:.|...|.:..:|.::.|.|              :::|:||......||.|:|||:....||:
Human   266 SSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFF 330

  Fly    87 RNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPI 151
            |||.:|:.|||::.|.:::||.|:..:::....:|.:.:.|::|.|.:|.|:.|.: ...|.|..
Human   331 RNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRL-EPESEYYK 394

  Fly   152 TQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGG 216
            .:||.|.|.||||.::|..:.|:|.|||:|..|.|||....|.|||..|..    |||||.:..|
Human   395 LRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAH----SNLNGVWYRG 455

  Fly   217 NHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            .|. .:.:..|:.|.|::|.:||.|.|.:|:||
Human   456 GHY-RSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	80/228 (35%)
ANGPTL2	NP_036230.1	FReD	273..487	CDD:238040	75/219 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40314
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810