Protein Alignment CG5550 and FCN1

DIOPT Version :9

• Sequence 1: NP_001246376.1
• Gene: CG5550 / 36883
• FlyBaseID: FBgn0034160
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_001994.2
• Gene: FCN1 / 2219
• HGNCID: 3623
• Length: 326
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 89/233 - (38%)
• Similarity: 131/233 - (56%)
• Gaps: 13/233 - (5%)

  Fly    22 EIGENVKIQTYKKYSSSCKELNPK---KSGVQKIQV-GSDVIEVYCDVTIAGKGWLVVQRRVSVE 82
            |.|:..:.|:......:||:|..:   .||...|.: ....:.|.||:...|.||.|.|||:...
Human   101 EKGDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGS 165

  Fly    83 ENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYS 147
            .:|||:|.:|:.|||...|.|::|.:|::.:::....||.::||||.|..::|.|..|.|.:...
Human   166 VDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAE 230

  Fly   148 NYPITQLGAY-SGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNG 211
            .|.:. |||: .|:||:||:.|....|||.|:|||.::.|||.::.|||||.:|    ..|||||
Human   231 KYKLV-LGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADC----HASNLNG 290

  Fly   212 AYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            .||.|.|..   :.:||.|...||:.||||...:.|||
Human   291 LYLMGPHES---YANGINWSAAKGYKYSYKVSEMKVRP 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	86/221 (39%)
FCN1	NP_001994.2	Collagen	51..107	CDD:189968	2/5 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	72..111		3/9 (33%)
		FReD	115..325	CDD:238040	84/217 (39%)
		A domain, contributes to trimerization	115..154		10/38 (26%)
		B domain, contributes to trimerization	155..243		32/88 (36%)
		Carbohydrate-binding. /evidence=ECO:0000269|PubMed:17897951	282..284		1/5 (20%)
		P domain. /evidence=ECO:0000303|PubMed:17148457	317..326		4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1518
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3915
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.860