DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Angptl2

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_598253.2	Gene:	Angptl2 / 171100	RGDID:	620004	Length:	493	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	79/228 - (34%)
Similarity:	126/228 - (55%)	Gaps:	20/228 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SSSCKELNPKKSGVQKIQVG--------------SDVIEVYCDVTIAGKGWLVVQRRVSVEENFY 86
            ||:.|...|.:..:|.::.|              :.:::|:||......||.|:|||:....||:
  Rat   266 SSTDKPSGPWRDCLQALEDGHSTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFF 330

  Fly    87 RNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPI 151
            |||.:|:.|||::.|.:::||.|:..:::....:|.:.:.|::|.|.:|.|:.|.: ...|.|..
  Rat   331 RNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRL-EPESEYYK 394

  Fly   152 TQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGG 216
            .:||.|.|.||||.::|..:.|:|.|||:|..|.|||....|.|||..|..    |||||.:..|
  Rat   395 LRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAH----SNLNGVWYRG 455

  Fly   217 NHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            .|. .:.:..|:.|.|::|.:||.|.|.:|:||
  Rat   456 GHY-RSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	79/228 (35%)
Angptl2	NP_598253.2	t_SNARE	156..>206	CDD:197699
Angptl2	NP_598253.2	FReD	273..487	CDD:238040	74/219 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm12326
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810