DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Fgl2

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_032039.2	Gene:	Fgl2 / 14190	MGIID:	103266	Length:	432	Species:	Mus musculus

Alignment Length:	238	Identity:	83/238 - (34%)
Similarity:	120/238 - (50%)	Gaps:	31/238 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 YKKYSSSCKE---LNPKKSGVQKIQVG--SDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTS 91
            ||    .|.:   |..:.||..::...  :...|||||:...|.||.|:|.|:....||.|.|..
Mouse   203 YK----DCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKD 263

  Fly    92 YQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGA 156
            |:.|||:|:..|::|.:.::.::..:...|.|:|.||.|...||.|..|:|.|.:..|.: .:|.
Mouse   264 YKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRL-HIGN 327

  Fly   157 YSGTAGDSLSY-----HLYQPFSTFDRDNDN-ATINCAARYMGAWWYRECLSRIPCSNLNGAYLG 215
            |:|||||:|.:     |..:.|:|.|||||. .:.||...|...||:..|||    :||||.|.
Mouse   328 YNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLS----ANLNGKYY- 387

  Fly   216 GNHTDPALFGSGIVWGEWK--------GFTYSYKTVNIMVRPK 250
              |.......:||.||.|.        |:..|:|...:|:|||
Mouse   388 --HQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	79/234 (34%)
Fgl2	NP_032039.2	Uds1	72..151	CDD:292096
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..122
		Fibrinogen_C	202..428	CDD:278572	81/236 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810