DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Fga

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_001104518.1	Gene:	Fga / 14161	MGIID:	1316726	Length:	789	Species:	Mus musculus

Alignment Length:	234	Identity:	86/234 - (36%)
Similarity:	118/234 - (50%)	Gaps:	33/234 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LNPKKSGVQ------KIQVGSDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDL- 99
            |..:.||.|      |....|.|..||||...:..|||::|:|:....||.|.|..|:.|||.|
Mouse   559 LQTQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLN 623

  Fly   100 ---KGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTA 161
               :|.|::| |:...:.:|:...|.:||.|:||::.||.|. |.||:....|.: |:.:|.|||
Mouse   624 DKGEGEFWLG-NDYLHLLTLRGSVLRVELEDWAGKEAYAEYH-FRVGSEAEGYAL-QVSSYRGTA 685

  Fly   162 GDSL-----------SYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLG 215
            ||:|           :.|....|||||||.|....|||..|.|.|||..|    ..:||||.|..
Mouse   686 GDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSC----QAANLNGIYYP 746

  Fly   216 GNHTDPA-----LFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            |...||.     ...:|:||..::|..||.:.|.:.:||
Mouse   747 GGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRP 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	86/234 (37%)
Fga	NP_001104518.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	263..420
		Fibrinogen_aC	392..457	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..555
		FReD	550..786	CDD:238040	86/234 (37%)
		Fib_alpha	51..190	CDD:285864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810