DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5550 and Angpt4

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_033771.1	Gene:	Angpt4 / 11602	MGIID:	1336887	Length:	509	Species:	Mus musculus

Alignment Length:	237	Identity:	73/237 - (30%)
Similarity:	112/237 - (47%)	Gaps:	29/237 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VKIQTYKKYSSSCKELNPKKSGVQKIQV-------GSDVIEVYCDVTIAGKGWLVVQRRVSVEEN 84
            |.::|.|.....|.|:  |:|||....|       .:..::|:||:...|.||.::|.|.....|
Mouse   285 VSLKTPKPVFQDCAEI--KRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVN 347

  Fly    85 FYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNY 149
            |.|.|..|:.|||::....::|...:::::|.....|.:||.|:.|.:....|..|.:|:....|
Mouse   348 FQRTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRY 412

  Fly   150 PITQLGAYSGTAG--DSLSYHLYQP----FSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSN 208
            .:: :...|.:||  :||:     |    |||.|.||||....||....|.||:..|    ..||
Mouse   413 SLS-VNDSSSSAGRKNSLA-----PQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDAC----GLSN 467

  Fly   209 LNGAYLG-GNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
            |||.|.. ..|....   :||.|..::|.:||.....:|:||
Mouse   468 LNGIYYSVHQHLHKI---NGIRWHYFRGPSYSLHGTRMMLRP 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	70/230 (30%)
Angpt4	NP_033771.1	BMFP	140..217	CDD:294701
		FReD	292..507	CDD:238040	70/230 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..436		6/24 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810