DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5550 and tnc

DIOPT Version :9

Sequence 1:	NP_001246376.1	Gene:	CG5550 / 36883	FlyBaseID:	FBgn0034160	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	XP_004916768.1	Gene:	tnc / 100494697	XenbaseID:	XB-GENE-1002816	Length:	1829	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	98/244 - (40%)
Similarity:	135/244 - (55%)	Gaps:	34/244 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SLGLFYLASAEIGENVKIQTYKKYSSSCKE--LNPK-KSGVQKIQVGSD---VIEVYCDVTIAGK 70
            ::||.|                .|...|.:  ||.: .||:..|.|..|   .:|||||:::.|.
Frog  1601 TIGLLY----------------PYPKDCSQALLNGEADSGLYTIYVNGDQSQPMEVYCDMSVDGG 1649

  Fly    71 GWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYA 135
            ||:|..||....|.|||||.:|..|||::...||:||.||:|::||...||.::|.| ..|..||
Frog  1650 GWIVFLRRTDGSEEFYRNWKTYSAGFGNINNEFFMGLENLHKLTSLGQYELRVDLRD-NDETAYA 1713

  Fly   136 HYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYREC 200
            .|..|.||:..|.:.: ::..||||||||::||..:.|||||:|||:|..|||..|.||:||:.|
Frog  1714 VYDKFSVGDAKSRFRL-KVEGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNC 1777

  Fly   201 LSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249
             .|:   ||.|.|...||:      .|:.|..|||..||.:...:.:||
Frog  1778 -HRV---NLMGRYGDTNHS------QGVNWFHWKGHEYSIQFAEMKIRP 1816

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	95/222 (43%)
tnc	XP_004916768.1	EGF_Tenascin	187..214	CDD:376143
		EGF_Tenascin	249..276	CDD:376143
		EGF_Tenascin	280..307	CDD:376143
		DSL	<295..337	CDD:366627
		EGF_Tenascin	342..369	CDD:376143
		EGF_Tenascin	373..399	CDD:376143
		EGF_Tenascin	404..431	CDD:376143
		EGF_Tenascin	435..461	CDD:376143
		EGF_Tenascin	466..492	CDD:376143
		EGF_Tenascin	497..524	CDD:376143
		EGF_Tenascin	528..554	CDD:376143
		EGF_Tenascin	559..586	CDD:376143
		EGF_Tenascin	590..617	CDD:376143
		fn3	620..691	CDD:365830
		fn3	713..789	CDD:365830
		fn3	799..877	CDD:365830
		fn3	887..969	CDD:365830
		fn3	979..1056	CDD:365830
		fn3	1074..1147	CDD:365830
		fn3	1158..1230	CDD:365830
		fn3	1249..1329	CDD:365830
		fn3	1339..1418	CDD:365830
		fn3	1428..1506	CDD:365830
		fn3	1518..1594	CDD:365830
		FReD	1607..1817	CDD:238040	95/222 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9330
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000