Protein Alignment CG5522 and ralgps2

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_031756835.1
• Gene: ralgps2 / 779506
• XenbaseID: XB-GENE-990039
• Length: 610
• Species: Xenopus tropicalis
• Alignment Length: 668
• Identity: 247/668 - (36%)
• Similarity: 336/668 - (50%)
• Gaps: 165/668 - (24%)

  Fly   132 TIAASAA-PPSKSQSLPAHASI---KQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSS 192
            |:.|:|: ..|.|:||....|.   |..|||:...|.|..:..|.||||:|.|||..|||:||||
 Frog    11 TLPATASEKSSSSESLSDKGSSELKKSFDAVVFDVLMVTPEEYAGQITLMDVPVFKAIQPEELSS 75

  Fly   193 CAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSL 257
            |.|.||:|:.:.||.||||:|||..|||.|:|||:|:..|.|||:::|:||.||||:||||||||
 Frog    76 CGWNKKEKYSSAPNAVAFTRRFNQVSFWVVREILHAQTLKIRAEVLSHYIKTAKKLYELNNLHSL 140

  Fly   258 FAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRL-PCIPYLGLF 321
            .:::|.:|||.|:|||||||.||:||:..|::|..:.|.:||:..||.|:.||:: |||||||::
 Frog   141 MSVVSGLQSAPIFRLTKTWALLSRKDKATFEKLEYVVSKEDNYKRLRDYINSLKMTPCIPYLGIY 205

  Fly   322 LTDLIYIDLAHPHKGG-LEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQ 385
            |:||.|||.|:|..|. ||.|||.|.||||||:||:.|||....:......||||.|:|||||||
 Frog   206 LSDLTYIDSAYPSTGSILENEQRSNLMNNILRIISDLQQSCEYDIPLLSHVQKYLNSVRYIEELQ 270

  Fly   386 NIFEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKTI---GSM---RMA 444
            ...|:|.||.||.:||.: |.|.::  :|||    ::|.|.:|....|..|:|   |.:   ...
 Frog   271 KFVEDDNYKLSLKIEPGT-STPRTA--ASKE----DLVGPEVGASPTSSRKSIPVEGVLLPPTPP 328

  Fly   445 SGTKFVP-GHRKCRSLG---------TKFRSSSLPRNFAEKCQCCIVMIAPGIGTISNKRCRCRR 499
            |....:| |||||.|||         .:|:|::.|
 Frog   329 SPRNLIPHGHRKCHSLGYNFIHKMNSAEFKSATFP------------------------------ 363

  Fly   500 IFGKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDSVLE-HSDALSQADLTSLESAEGI----- 558
                                     ...|| |||||||:| |:.:..||:.::|.|...|
 Frog   364 -------------------------NAGPR-HLLDDSVMEPHTPSRGQAESSTLSSGISIGSSDG 402

  Fly   559 ----------------------------------------------------MCDFTGSDCDLMS 571
                                                                |..|:.| |.|:.
 Frog   403 SELSEDMPWPAFERNRLYHSLGPMTRGSWNGYRGPVKASRTPRAQLSMGRLKMPSFSLS-CVLLQ 466

  Fly   572 PEAAA--------------AMHGCVRRKTVQKEGRKPAVASWQRYWLQIWANSLVYFPPKSFKGS 622
            ..::|              |:.|.:|||||.|||:||.||||.:||..:....|:|:..||.|.:
 Frog   467 SSSSAETTDLAVHLCPEEVAIQGVLRRKTVLKEGKKPTVASWTKYWAVLCGTQLIYYAAKSLKAT 531

  Fly   623 ERNDFKREPCKVCPLDGWYAHVSDNTKHKNTFELCHRTLGTVYRFRTDSPQMTHLW---SNAICK 684
            ||..||....|...:.||.|.::|:.:|.:.|.|.....|..|:|:..|.....||   .:|.|:
 Frog   532 ERKHFKAISTKNISVVGWMAMMADDPEHPDIFLLTDSEKGNSYKFQAGSRMNAMLWFKHLSAACQ 596

  Fly   685 LATMRVPKPLPTNLMSFE 702
            ....:|    |.|||:||
 Frog   597 SNRQQV----PANLMTFE 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	136/238 (57%)
		PH_RalGPS1_2	578..692	CDD:270120	43/116 (37%)
		PH	578..685	CDD:278594	42/109 (39%)
ralgps2	XP_031756835.1	RasGEF	45..286	CDD:214539	136/240 (57%)
		PH_RalGPS1_2	487..601	CDD:270120	42/113 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	214	1.000	Domainoid score	I2686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	378	1.000	Inparanoid score	I2030
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D184404at33208
OrthoFinder	1	1.000	-	-		FOG0003356
OrthoInspector	1	1.000	-	-		otm49073
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2715
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.060