Protein Alignment RalGPS and rasgrf1

DIOPT Version :10

• Sequence 1: NP_725613.1
• Gene: RalGPS / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_073786440.1
• Gene: rasgrf1 / 568885
• ZFINID: ZDB-GENE-090311-28
• Length: 1264
• Species: Danio rerio
• Alignment Length: 381
• Identity: 101/381 - (26%)
• Similarity: 173/381 - (45%)
• Gaps: 46/381 - (12%)

  Fly    25 PTTDYNGYTGQAYAATQFKQSSPPPPPSQQQQQPTRVSKQRSPN--TNGSAHTMACLRQE-KTYK 86
            ||.:  .|...:.|:|.|       |..|:......|.::.:.|  .|...|.::...|: :|..
Zfish   908 PTKE--KYRRMSLASTGF-------PTDQRNGDKEFVIRRAATNRVLNVLRHWVSKHSQDFETNT 963

  Fly    87 EQQMEPPSMQPQASKTLNIKSTRRKNSIGCLNSFSSSPDSPG----CYYTIAASAAPPSKSQSLP 147
            |.:|:..|...:......:.:..||.:...:.:.:.  :.||    |...: ...|...||:|..
Zfish   964 ELKMKVISFLEEVMHDPELLTQERKAAANIIRTLTQ--EDPGDNQICLEEV-LQMAEGGKSESFE 1025

  Fly   148 AHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTK 212
            .|::::                :|.|:||||..||..|..:|.....|.|.||:..||.|:..||
Zfish  1026 NHSALE----------------IAEQLTLLDHLVFKVIPYEEFFGQGWMKNDKNEKTPYIMKTTK 1074

  Fly   213 RFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWA 277
            .||..|.....|||..|....|..::..::.||.....|:|.:::..|.|::..:||:||.|||.
Zfish  1075 HFNDISDLIATEILRCEDVNVRVAVMEKWVAVADICRCLHNYNAVLEITSSLNRSSIFRLKKTWL 1139

  Fly   278 CLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPH--KGGLEP 340
            .:||:.:...|:|..:.|.:..:.|||..|::...||:||||::||||.:|:...|:  :..|..
Zfish  1140 KVSKQTKTVIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDNLVN 1204

  Fly   341 EQRRNKMNNILRVISNYQQSNYK---------HLQKHEATQKYLTSIRYIEELQNI 387
            ..:...:::|:|.|..:||:.||         :|....|..:...|.|:...:|.:
Zfish  1205 FSKMRMISHIIREIRQFQQTAYKIDYQPKAALYLLDRSAVMEEEGSTRHPHNVQTL 1260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RalGPS	NP_725613.1	RasGEF	169..335	CDD:459872	61/167 (37%)
		PH_RalGPS1_2	578..692	CDD:270120
rasgrf1	XP_073786440.1	None