Protein Alignment CG5522 and sos2

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001334612.1
• Gene: sos2 / 561670
• ZFINID: ZDB-GENE-090319-5
• Length: 1341
• Species: Danio rerio
• Alignment Length: 661
• Identity: 136/661 - (20%)
• Similarity: 233/661 - (35%)
• Gaps: 175/661 - (26%)

  Fly    47 PPPPPSQQQ-------QQPTRVSKQRSPNTNGSAHTMACLRQEKTYKEQQMEPPSMQPQ------ 98
            |.|.||:..       :||.....||..........:..|...:.:.|.........|:
Zfish   646 PEPEPSEADREALWNGEQPMAAELQRFRREYVQPVQLRVLNVFRQWVEHHFYDFENDPELYERLE 710

  Fly    99 ----ASKTLNIKSTRR-KNSIGCLNSFSSSPDSPGCYYTIAASAAPPSKSQSLPAHASIKQLDAV 158
                ::..|..||.|: ..||..:........|.|..:.|...:.||.....:.....:...|.:
Zfish   711 GYLISTTQLRGKSMRKWVESISKIMRRKIQMQSNGISHNITFESPPPPIEWHISRPGQVDTFDLM 775

  Fly   159 ILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQ 223
            .|..:.:     |.|:|||:..::..::|.||....|||:||..|:||::...:...:.:.|..:
Zfish   776 TLHPIEI-----ARQLTLLESDLYRAVRPSELVGSVWTKEDKEKNSPNLLRMIRHTTNLTLWFEK 835

  Fly   224 EILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFD 288
            .|:.||...:|..:.:..|::.:...||||.:.:..|:||:.|..:|||..|:..:.::.|...:
Zfish   836 CIVEAENVDERVAVFSRIIEILQVFQELNNFNGVLEIVSAINSVPVYRLDHTFEAVPERKRRILE 900

  Fly   289 RLSDIFSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHP---HKGGLE--PEQRRNKMN 348
            ...::  .||::....:.|:|:..||:|:.|::||:::..:..:|   .:.|.|  ...:|.|:.
Zfish   901 EAVEL--SQDHFKKYLAKLKSINPPCVPFFGIYLTNILKTEEGNPDFLKRDGKELINFSKRRKVA 963

  Fly   349 NILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQ---NIFEED----QYKRSLNLEPASPSG 406
            .|...|..||...|....:|:..       |:.|.|.   |:.|:|    .:.:||.:||.:...
Zfish   964 EITGEIQQYQNQPYCLKVEHDIK-------RFFENLNPMGNMNEKDFSDYLFNKSLEIEPRNSKQ 1021

  Fly   407 PSSSSCSSKESFNVEVVTPALGCLNLSPAKTIGSMRMASGTKFVPGHRKCR-SLGTKFRSSSLPR 470
            |                 |..      |.||..|::.       ||.|..| ::|
Zfish  1022 P-----------------PRF------PRKTTYSLKS-------PGVRPVRQAVG---------- 1046

  Fly   471 NFAEKCQCCIVMIAPGIGTISNKRCRCRRIFGKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDD 535
                           |.||:.                    |||       .|.:.:|.|.:...
Zfish  1047 ---------------GGGTLK--------------------GHP-------VPLEREPPHKITFR 1069

  Fly   536 SVLEHSDALSQADLTSLESAEGIMCDFTGSDCDLMSPEAAAAMHGCVRRKTVQKEGRKPAVASWQ 600
            |:.|.......:..||..:.              ..|::|::....|..:.....|.....|.
Zfish  1070 SIAETEPETPPSLPTSPNTP--------------TPPQSASSDFNSVFEQDFMPYGNNTIFAP-- 1118

  Fly   601 RYWLQIWANSLVYFPPKSFK----GSERNDFKREPCKVCPLDGWYAHVSDNTKHKNTFELCHRTL 661
                       |:.|...|:    ||.......||.|..||.   ....|.:..||:
Zfish  1119 -----------VFLPQSKFQSVSCGSLHQLMSDEPLKPPPLP---PRRKDTSSDKNS-------- 1161

  Fly   662 GTVYRFRTDSP 672
                  |:|||
Zfish  1162 ------RSDSP 1166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	64/248 (26%)
		PH_RalGPS1_2	578..692	CDD:270120	20/99 (20%)
		PH	578..685	CDD:278594	20/99 (20%)
sos2	NP_001334612.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810