Protein Alignment RalGPS and rapgef1a

DIOPT Version :10

• Sequence 1: NP_725613.1
• Gene: RalGPS / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_005166961.1
• Gene: rapgef1a / 558635
• ZFINID: ZDB-GENE-081105-26
• Length: 1085
• Species: Danio rerio
• Alignment Length: 281
• Identity: 79/281 - (28%)
• Similarity: 131/281 - (46%)
• Gaps: 51/281 - (18%)

  Fly   132 TIAAS--AAPPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCA 194
            |:||.  ||.|.......:|.                   :|:|:||||..:|.:|:..|:  ..
Zfish   831 TLAARGVAARPGTLHDFRSHE-------------------IADQLTLLDAELFYKIEIPEV--LL 874

  Fly   195 WTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFA 259
            |.|:.....:||:..||:.||:.|:|....|:..|:.:.|.:::..|||:.|.|.:|||.:|..|
Zfish   875 WAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIILQEKAQDREKLLLKFIKIMKHLRKLNNFNSYLA 939

  Fly   260 IISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRLPCIPYLGLFLTD 324
            |:||:.||.|.||  .|   .|:.....:....:.....::...|:.|..:..||||||||.|.|
Zfish   940 ILSALDSAPIRRL--EW---QKQTSEGLEEYCTLIDSSSSFRAYRAALADVEPPCIPYLGLILQD 999

  Fly   325 LIYIDLAHP-HKGGLEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQNIF 388
            |.::.|.:| |..|.....:|.:..|||..:..:||.:|              .:::.:::.:.|
Zfish  1000 LTFVHLGNPDHIEGKINFSKRWQQFNILDTMRRFQQVHY--------------DLKHNDDIVSFF 1050

  Fly   389 --------EEDQYKRSLNLEP 401
                    ||..::.||.::|
Zfish  1051 NDFSDHLAEEALWELSLKIKP 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RalGPS	NP_725613.1	RasGEF	169..335	CDD:459872	57/166 (34%)
		PH_RalGPS1_2	578..692	CDD:270120
rapgef1a	XP_005166961.1	PHA03247	<183..474	CDD:223021
		RasGEFN	696..837	CDD:214571	3/5 (60%)
		RasGEF	844..1073	CDD:214539	73/268 (27%)