| Sequence 1: | NP_725613.1 | Gene: | CG5522 / 36881 | FlyBaseID: | FBgn0034158 | Length: | 702 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_689876.2 | Gene: | RALGPS2 / 55103 | HGNCID: | 30279 | Length: | 583 | Species: | Homo sapiens |
| Alignment Length: | 642 | Identity: | 243/642 - (37%) |
|---|---|---|---|
| Similarity: | 331/642 - (51%) | Gaps: | 143/642 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 133 IAASAA-PPSKSQSLPAHAS--IKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCA 194
Fly 195 WTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFA 259
Fly 260 IISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESLRL-PCIPYLGLFLT 323
Fly 324 DLIYIDLAHPHKGG-LEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQNI 387
Fly 388 FEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKTIGS------MRMASG 446
Fly 447 TKFVP-GHRKCRSLG---------TKFRSSSLPRNFAEKCQCCIVMIAPGIGTISNKRCRCRRIF 501
Fly 502 GKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDSVLE-HSDALSQADLTSLESAEGIMCDFTGS 565
Fly 566 DCDLMSPE-----------------------------------------------AAAAMHGCVR 583
Fly 584 RKTVQKEGRKPAVASWQRYWLQIWANSLVYFPPKSFKGSERNDFKREPCKVCPLDGWYAHVSDNT 648
Fly 649 KHKNTFELCHRTLGTVYRFRTDSPQMTHLW---SNAICKLATMRVPKPLPTNLMSFE 702 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG5522 | NP_725613.1 | RasGEF | 163..400 | CDD:214539 | 137/238 (58%) |
| PH_RalGPS1_2 | 578..692 | CDD:270120 | 40/116 (34%) | ||
| PH | 578..685 | CDD:278594 | 39/109 (36%) | ||
| RALGPS2 | NP_689876.2 | RasGEF | 45..286 | CDD:214539 | 137/240 (57%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 283..314 | 11/37 (30%) | |||
| PXXP | 324..327 | 0/2 (0%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 372..406 | 13/37 (35%) | |||
| Required for stimulation of nucleotide exchange by RALA. /evidence=ECO:0000250 | 459..583 | 45/127 (35%) | |||
| PH_RalGPS1_2 | 459..574 | CDD:270120 | 39/114 (34%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 220 | 1.000 | Domainoid score | I2629 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3417 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 386 | 1.000 | Inparanoid score | I2036 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG49702 | |
| OrthoDB | 1 | 1.010 | - | - | D184404at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0003356 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41849 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104897 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR23113 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5234 |
| SonicParanoid | 1 | 1.000 | - | - | X2715 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.870 | |||||