Protein Alignment CG5522 and rgl1

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_991200.2
• Gene: rgl1 / 402933
• ZFINID: ZDB-GENE-040426-1816
• Length: 804
• Species: Danio rerio
• Alignment Length: 528
• Identity: 130/528 - (24%)
• Similarity: 192/528 - (36%)
• Gaps: 185/528 - (35%)

  Fly   116 CLNSFSSSPDSPGCYYTIA------ASAAPPSKSQSLPAHASIKQLDAVILSALRVPA------- 167
            |...|...|..|..:..:.      ..:.|..::|||             |..|||.|
Zfish   190 CPEDFQEPPSYPSLHRVLGFLQKAMPGSEPMRRAQSL-------------LEQLRVQASLENETE 241

  Fly   168 ------------------------------DVLANQITLLDFPVFAQIQPDELSSCAWT---KKD 199
                                          |::|.|:|.:|..:|.::.|.......|:   |||
Zfish   242 GGFQYINPFCLGEDEEVEIDLQEDFFSFEVDLVAEQLTYMDALLFKKVVPHHCLGSIWSQRDKKD 306

  Fly   200 KHVNTPNIVAFTKRFNHTSFWTVQEILNAEQ--PKQRAEIITHFIKVAKKLHELNNLHSLFAIIS 262
            ...:.|.|.|...:||..:...|..||...|  |..||.||..:|.:|::.....|..||.||:|
Zfish   307 GKQSAPTIRATITQFNAVTACVVSTILRQRQIRPHLRARIIQRWIDIAQECRIRKNFSSLRAIVS 371

  Fly   263 AMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYL-------------------- 307
            |:||..:|||.:|||.::|.....|:.||||||||:|:...|..|
Zfish   372 ALQSNPLYRLKRTWASVAKDSMQMFEELSDIFSDQNNYLTSRELLMREGTSKFASLDSCAKDHQK 436

  Fly   308 ---ESLRLP--------CIPYLGLFLTDLIYIDLAHPH--KGGL-EPEQRRNKMNNILRVISNYQ 358
               :.|:|.        .|||||.|||||..:|.|.|.  :||| ..|:||.:...|.::
Zfish   437 RSQKRLQLQKDMGAMQGTIPYLGTFLTDLTMLDTALPDQVEGGLINFEKRRREFEVIAQI----- 496

  Fly   359 QSNYKHLQKHEATQKYLTS-----IRYIEELQNIFEEDQYKRSLNLE------PASP-------- 404
                |.||  .|...|..:     :|:.:......||:.|..|..:|      |.||
Zfish   497 ----KLLQ--SACNSYCLTPDPAFLRWFKSQPQYSEEESYVLSCEVEGLGDNSPTSPKPRKSMVK 555

  Fly   405 -----------------------SGPSSSSCSSKESFNV----------EVVTP----------- 425
                                   |.|:.||..|.:|.:|          :.:||
Zfish   556 RLSLLFLGNDSTNTSSPVRESPRSPPTGSSGESMDSVSVSSSDSSPSESDGMTPTHSIDAHLKKL 620

  Fly   426 -------ALGCLNLSPAKTIGSMRMASGTKFVPG----HRKCRSLGTKFRSSS--LPRNFAEKCQ 477
                   :|..::.|.:....|:.:||.|  :||    ||:..||......:|  .|..:..:.|
Zfish   621 SESSSCNSLHSMDTSSSTASASISLASPT--LPGPPCNHRRSISLTPLMSPTSPGFPPAYNTQAQ 683

  Fly   478 -CCIVMIA 484
             .||:.::
Zfish   684 DACIIRVS 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	91/317 (29%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
rgl1	NP_991200.2	REM	109..232	CDD:100121	10/54 (19%)
		RasGEF	266..535	CDD:238087	87/279 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	564..611		9/46 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	640..676		11/37 (30%)
		RalGDS_RA	684..769	CDD:176351	2/8 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910