Protein Alignment RalGPS and C3G

DIOPT Version :10

• Sequence 1: NP_725613.1
• Gene: RalGPS / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Alignment Length: 287
• Identity: 76/287 - (26%)
• Similarity: 133/287 - (46%)
• Gaps: 54/287 - (18%)

  Fly   126 SPGCYYTIAASAAPPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDEL 190
            |.||..|....        :.|:...:|.|:             :|.|:||||..:|.:|:..|:
  Fly  1320 SGGCSGTAGGG--------NQPSLLDLKSLE-------------IAEQMTLLDAELFTKIEIPEV 1363

  Fly   191 SSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLH 255
              ..:.|......:||:..||:.||..|:|...:||..:..|:|.:.:..|||:.|.|.::||.:
  Fly  1364 --LLFAKDQCEEKSPNLNKFTEHFNKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYN 1426

  Fly   256 SLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYLESL---RLPCIPY 317
            |..|::||:.|..|.||  .|.....::..:|..|.|..|      :.|:|.::|   ..|||||
  Fly  1427 SYLALLSALDSGPIRRL--EWQKGITEEVRSFCALIDSSS------SFRAYRQALAETNPPCIPY 1483

  Fly   318 LGLFLTDLIYIDLAHPHKG-------GLEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYL 375
            :||.|.||.::     |.|       |:....:|.:..||:..:..:::..|. .:::|..
  Fly  1484 IGLILQDLTFV-----HVGNQDYLSKGVINFSKRWQQYNIIDNMKRFKKCAYP-FRRNERI---- 1538

  Fly   376 TSIRYIEELQNIF-EEDQYKRSLNLEP 401
              ||:.:..::.. ||:.::.|..::|
  Fly  1539 --IRFFDNFKDFMGEEEMWQISEKIKP 1563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RalGPS	NP_725613.1	RasGEF	169..335	CDD:459872	55/168 (33%)
		PH_RalGPS1_2	578..692	CDD:270120
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571
		RasGEF	1335..1558	CDD:238087	69/257 (27%)