Protein Alignment CG5522 and Rasgrp1

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_038960368.1
• Gene: Rasgrp1 / 29434
• RGDID: 3539
• Length: 818
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 103/524 - (19%)
• Similarity: 184/524 - (35%)
• Gaps: 173/524 - (33%)

  Fly   143 SQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDE-----LSSCAWTKKDKHV 202
            :|.:.::.|.|:..:::...|.  .:.|:..:|.|:|..|.:|...:     ::||.       .
  Rat   207 TQRIKSNTSKKRKVSLLFDHLE--PEELSEHLTYLEFKSFRRISFSDYQNYLVNSCV-------K 262

  Fly   203 NTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSA 267
            ..|.:.......|..|.|....:|:...|:.|||:...||.||:|||:|.|.::|.|:|..:..:
  Rat   263 ENPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFIKFIHVAQKLHQLQNFNTLMAVIGGLCHS 327

  Fly   268 SIYRLTKTWACLSKKDRNAFDRLSDIFSDQDNWANL-RSYLESLRLPCIPYLGLFLTDLIYIDLA 331
            ||.||.:|.:.:..:.......::::.|...|:.|. |:|.|..... ||.||:.|.|||.:..|
  Rat   328 SISRLKETSSHVPHEINKVLGEMTELLSSCRNYDNYRRAYGECTHFK-IPILGVHLKDLISLYEA 391

  Fly   332 HPHKGGLEPEQRRNKMNNILRVISNYQQSNYKHLQKHEATQKYLTSIRYIEE------------- 383
            .|                      :|.:....::||..|...::..:..:::
  Rat   392 MP----------------------DYLEDGKVNVQKLLALYNHINELVQLQDVAPPLDANKDLVH 434

  Fly   384 -----LQNIFEEDQ-YKRSLNLEPASPSGPSSSSCSSKESFNVEVVTPALGCLNLSPAKTIGSMR 442
                 |...:.||: |:.|...||.:...|.                       |:|:|....:.
  Rat   435 LLTLSLDLYYTEDEIYELSYAREPRNHRAPP-----------------------LTPSKPPVVVD 476

  Fly   443 MASGT------KFVPGHRKCRSLGTKFR------------------SSSLPRNFAEKCQCCIVMI 483
            .|||.      |.:..|.: |.:.:.|:                  ::|.|.:|.       ||.
  Rat   477 WASGVSPKPDPKTISKHVQ-RMVDSVFKNYDLDQDGYISQEEFEKIAASFPFSFC-------VMD 533

  Fly   484 APGIGTISNKR-----CRCRRIFGKIATHNHSDGHPHHLHLELDPSQVQPRHHLLDDSVLEHSDA 543
            ....|.||...     .|...|:.|:..     |.||:..   :.:.::|
  Rat   534 KDREGLISRDEITAYFMRASSIYSKLGL-----GFPHNFQ---ETTYLKP--------------- 575

  Fly   544 LSQADLTSLESAEGIM---------CDFTGSDC-----DLMSPEAAAAMHGCVRRKTVQKEGRKP 594
                  |..::..|.:         |...|.:|     ||:..|.             :|..:.|
  Rat   576 ------TFCDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFEC-------------KKRSKSP 621

  Fly   595 AVAS 598
            ||::
  Rat   622 AVST 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	60/261 (23%)
		PH_RalGPS1_2	578..692	CDD:270120	4/21 (19%)
		PH	578..685	CDD:278594	4/21 (19%)
Rasgrp1	XP_038960368.1	RasGEFN	77..199	CDD:214571
		RasGEF	224..460	CDD:214539	62/267 (23%)
		EF-hand_7	501..550	CDD:404394	9/55 (16%)
		C1_RASGRP1	563..617	CDD:410410	11/90 (12%)
		cc_RasGRP1_C	760..814	CDD:412086

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810