Protein Alignment CG5522 and Rgl1

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001099427.2
• Gene: Rgl1 / 289080
• RGDID: 1308947
• Length: 803
• Species: Rattus norvegicus
• Alignment Length: 442
• Identity: 121/442 - (27%)
• Similarity: 191/442 - (43%)
• Gaps: 88/442 - (19%)

  Fly    78 CLRQEKTYKEQQMEPPSMQPQASKTLNIKSTRRKNSI----GCLNSFSSSPDSPGCYYTIAASAA 138
            ||::...|.:|.|  |...|: .:..|:....:|..:    |.||:.|.||:
  Rat   202 CLQKLLEYLKQMM--PGSDPE-RRAQNLLEQFQKQDVDSDNGLLNTISFSPE------------- 250

  Fly   139 PPSKSQSLPAHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVN 203
               :.:.|.:..|.:        ......|::|.|:|.:|..:|.::.|.....|.|:::|:..|
  Rat   251 ---EEEELESGGSAE--------LTTFSEDLVAEQLTYMDAQLFKKVVPHHCLGCVWSRRDRKEN 304

  Fly   204 ---TPNIVAFTKRFNHTSFWTVQEILNAEQPK--QRAEIITHFIKVAKKLHELNNLHSLFAIISA 263
               .|.|.|...:||..:...|..||.::..|  |||.:|..:|.:|.:...|.|..||.||:||
  Rat   305 KHLAPTIRATISQFNALTKCVVSTILGSKDLKTQQRARVIEKWINIAHECRILKNFSSLRAIVSA 369

  Fly   264 MQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDN---------------WANLRSYLES---- 309
            :||.|||||.|.||.:.|.....|:.||:||||.:|               :|||.|.::.
  Rat   370 LQSNSIYRLKKAWAAVPKDRMLMFEELSEIFSDHNNHLTSRELLMKEGTSKFANLDSSVKENQKR 434

  Fly   310 ----LRLP--------CIPYLGLFLTDLIYIDLAHPH--KGGLEPEQRRNKMNNILRVISNYQQS 360
                |:|.        .:||||.|||||..:|.|...  :|||...::|.:...::..|...|.:
  Rat   435 TQRRLQLQKDMGVMQGTVPYLGTFLTDLTMLDTALQDYIEGGLINFEKRRREFEVIAQIKLLQSA 499

  Fly   361 NYKHLQKHEATQKYLTSIRYIEELQNIFEEDQYKRSLNLEPASPSGPSSSSCSSKESFNVEVVTP 425
            ...:....:  ||:   |::.:..|.:.||:.|..|..:|.|:.:  |::|...::|....:...
  Rat   500 CNSYCMSPD--QKF---IQWFQRQQLLTEEESYALSCEIEAAADA--STTSPKPRKSMVKRLSLL 557

  Fly   426 ALGCLNLSPAKTIGSMRMASGTKFVPGHRKCRSLGTKFRS---SSLPRNFAE 474
            .||. :|.|..|        .||..|......|.|....|   ||...|.:|
  Rat   558 FLGS-DLIPGST--------PTKEQPKSTASGSSGESMDSVSVSSCESNHSE 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	84/274 (31%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
Rgl1	NP_001099427.2	RasGEFN	100..231	CDD:214571	8/31 (26%)
		RasGEF	263..532	CDD:238087	84/273 (31%)
		RA_RGL	682..768	CDD:340730

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910