Protein Alignment CG5522 and RAPGEF1

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_011516871.1
• Gene: RAPGEF1 / 2889
• HGNCID: 4568
• Length: 1278
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 75/244 - (30%)
• Similarity: 125/244 - (51%)
• Gaps: 36/244 - (14%)

  Fly   170 LANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQR 234
            :|.|:||||..:|.:|:..|:  ..|.|:.....:||:..||:.||:.|:|....|:..|:.:.|
Human  1045 IAEQLTLLDAELFYKIEIPEV--LLWAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDR 1107

  Fly   235 AEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQDN 299
            ..::..|||:.|.|.:|||.:|..||:||:.||.|.||  .|      .:...:.|::..:..|:
Human  1108 ERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRL--EW------QKQTSEGLAEYCTLIDS 1164

  Fly   300 WANLRSY---LESLRLPCIPYLGLFLTDLIYIDLAHP-HKGGLEPEQRRNKMNNILRVISNYQQS 360
            .::.|:|   |..:..||||||||.|.||.::.|.:| :..|.....:|.:..|||..:..:||:
Human  1165 SSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRWQQFNILDSMRCFQQA 1229

  Fly   361 NYKHLQKHEATQKYLTSIRYIEELQNIF--------EEDQYKRSLNLEP 401
            :|              .:|..:::.|.|        ||..::.||.::|
Human  1230 HY--------------DMRRNDDIINFFNDFSDHLAEEALWELSLKIKP 1264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	74/241 (31%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
RAPGEF1	XP_011516871.1	RasGEFN	889..1030	CDD:214571
		RasGEF	1037..1266	CDD:214539	75/244 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810