Protein Alignment RalGPS and Rasgrp3

DIOPT Version :10

• Sequence 1: NP_725613.1
• Gene: RalGPS / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_997129.1
• Gene: Rasgrp3 / 240168
• MGIID: 3028579
• Length: 691
• Species: Mus musculus
• Alignment Length: 269
• Identity: 77/269 - (28%)
• Similarity: 121/269 - (44%)
• Gaps: 50/269 - (18%)

  Fly   170 LANQITLLDFPVFAQIQPDELSSCAWTKKDKHV------NTPNIVAFTKRFNHTSFWTVQEILNA 228
            ||..:|.|:...|.:|        ::|....:|      |.|.:......||..|.|....:|:.
Mouse   156 LAEHLTFLEHKSFRRI--------SFTDYQSYVIHGCLENNPTLERSIALFNGISKWVQLMVLSK 212

  Fly   229 EQPKQRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDI 293
            ...:||||:||.||.||:||.:|.|.::|.|::..:..:||.||..|.:.||.:....::.::::
Mouse   213 PSAQQRAEVITKFINVAQKLLQLKNFNTLMAVVGGLSHSSISRLKDTHSHLSSEVTKNWNEMTEL 277

  Fly   294 FSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPHKGGLEPEQRRNKMNNILRVISNYQ 358
            .|...|:.|.|..........||.||:.|.|||.:.:..|      .....||:|    |:..:|
Mouse   278 VSSNGNYCNYRKAFADCDGFKIPILGVHLKDLIAVHVIFP------DWMEENKVN----VVKMHQ 332

  Fly   359 QSNYKHLQKHEATQKYLTSIR----YIE---ELQNIF---------EEDQYKRSLNLEPA-SPSG 406
            .|         .|...|.|::    ::|   :|.|:.         |:|.||.||.|||. |.|.
Mouse   333 LS---------VTLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQ 388

  Fly   407 PSSSSCSSK 415
            |:|.:..:|
Mouse   389 PTSPTTPNK 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RalGPS	NP_725613.1	RasGEF	169..335	CDD:459872	51/170 (30%)
		PH_RalGPS1_2	578..692	CDD:270120
Rasgrp3	NP_997129.1	REM	11..126	CDD:100121
		RasGEF	148..384	CDD:214539	72/254 (28%)
		FRQ1	<403..478	CDD:444056
		C1_RASGRP3	488..546	CDD:410412