Protein Alignment CG5522 and Ralgds

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_006497859.1
• Gene: Ralgds / 19730
• MGIID: 107485
• Length: 908
• Species: Mus musculus
• Alignment Length: 514
• Identity: 123/514 - (23%)
• Similarity: 200/514 - (38%)
• Gaps: 155/514 - (30%)

  Fly    88 QQMEP-----PSMQPQASKTLNIKSTRRKNSIGCLNSFSSSPDSPGCYYTIAASAAPPSKSQSLP 147
            |:.||     |.::|..|::|.::|.                       .:...|..||.|....
Mouse   324 QEPEPSLALAPELEPAVSQSLELESA-----------------------PVPTPALEPSWSLPEA 365

  Fly   148 AHASIKQLDAVILSALRVPADVLANQITLLDFPVFAQIQPDELSSCAWTKKDK----HVNTPNIV 208
            ....:.:...::|    .|.|::|.|.||:|..:|.::.|.......|:::||    |: .|.|.
Mouse   366 TENGLTEKPHLLL----FPPDLVAEQFTLMDAELFKKVVPYHCLGSIWSQRDKKGKEHL-APTIR 425

  Fly   209 AFTKRFNHTSFWTVQEILNAEQPK--QRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYR 271
            |...:||:.:...:...|..:..|  .||.::.|:|:||::...|.|..||:||:||:||.:|:|
Mouse   426 ATVAQFNNVANCVITTCLGDQSMKAPDRARVVEHWIEVARECRALKNFSSLYAILSALQSNAIHR 490

  Fly   272 LTKTWACLSKKDRNAFDRLSDIFSDQDNWANLRSYL--------ESLRL---------------- 312
            |.|||..:|:.....|.:||:||||::|::..|..|        .:|.:
Mouse   491 LKKTWEEVSRDSFRVFQKLSEIFSDENNYSLSRELLIKEGTSKFATLEMNPRRAQRRQKETGVIQ 555

  Fly   313 PCIPYLGLFLTDLIYIDLAHPH--KGGLEPEQRRNKMNNILRVISNYQQ--SNYKHL-QKHEATQ 372
            ..:||||.|||||:.:|.|...  .|.|...::|.|...::..|...|.  :||... ::|..|
Mouse   556 GTVPYLGTFLTDLVMLDTAMKDYLYGRLINFEKRRKEFEVIAQIKLLQSACNNYSIAPEEHFGT- 619

  Fly   373 KYLTSIRYIEELQNIFEEDQYKRSLNLEPASPS---------------------GPS-----SSS 411
                   :...::.:.|.:.|..|..|||.|.|                     .||     |||
Mouse   620 -------WFRAMERLSEAESYTLSCELEPPSESASNTLRSKKSTAIVKRWSDRQAPSTELSTSSS 677

  Fly   412 CSSKESFNVEVVTPALGCLNLSPAKTIGSMRMAS------GTKFVP------------------- 451
            ..||....:. .:|.||..:::.|.::.|...:|      ...|||
Mouse   678 AHSKSCDQLR-CSPYLGSGDITDALSVHSAGSSSSDVEEINMSFVPESPDGQEKKFWESASQSSP 741

  Fly   452 --------------------------GHRKCRSLGTKFRSSSLPRNFAEKCQCCIVMIA 484
                                      .|::..| |....|||||....:...|||:.::
Mouse   742 ETSGISSASSSTSSSSASTTPVSTTRTHKRSVS-GVCSYSSSLPLYNQQVGDCCIIRVS 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	78/271 (29%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
Ralgds	XP_006497859.1	RasGEFN	112..249	CDD:214571
		RasGEF	376..643	CDD:214539	82/279 (29%)
		RA_RalGDS	792..877	CDD:340729	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910