Protein Alignment CG5522 and rasgrf2

DIOPT Version :9

• Sequence 1: NP_725613.1
• Gene: CG5522 / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_002942408.2
• Gene: rasgrf2 / 100486502
• XenbaseID: XB-GENE-483993
• Length: 1232
• Species: Xenopus tropicalis
• Alignment Length: 435
• Identity: 113/435 - (25%)
• Similarity: 178/435 - (40%)
• Gaps: 105/435 - (24%)

  Fly    39 ATQFKQSSP---PPPPSQQQQQPTRVSKQRSPNTNG------SAHTMA----------------- 77
            :|...::||   |..|...:.:||.|  |.|.|..|      ||..:|
 Frog   835 STDTAENSPCRSPSTPRHLRYRPTGV--QASDNQRGCSVSPASAFAIATAGAGHGSPPGFNNMER 897

  Fly    78 -C-----LRQEKTYK------------------------------EQQMEPPSMQPQASKTLNIK 106
             |     :|:..|.:                              |..:..|.:.||
 Frog   898 ICDKEFIIRRAATNRVLNVLRHWVSKHAQDFELNHEIKMNVVNLLEDVLRDPDLLPQ-------- 954

  Fly   107 STRRKNSIGCLNSFSSSPDSPGCYYT----IAASAAPPSKSQSLPAHASIKQLDAVILSALRVPA 167
              .||.:...|::.|.. :...|:..    |..|.:|.|:...             .|||:.
 Frog   955 --ERKAATNILSALSQE-EQDDCHLVLEDIINMSESPSSECLE-------------TLSAME--- 1000

  Fly   168 DVLANQITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPK 232
              ||.||||||..||..|...|.....|.|.||...||.|:..::.||..|.....||:......
 Frog  1001 --LAEQITLLDHIVFRSIPYQEFLGQGWMKPDKSERTPYIMKTSQHFNDMSNLVASEIMKHPDVP 1063

  Fly   233 QRAEIITHFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTWACLSKKDRNAFDRLSDIFSDQ 297
            .||..|..::.||.....::|.:.:..|.||:..:::|||.||||.:||:.:...|:|....|.:
 Frog  1064 SRASSIEKWVVVADICRCMHNYNGVLEITSALNRSAVYRLKKTWAKVSKQTKALMDKLQKTVSSE 1128

  Fly   298 DNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPH--KGGLEPEQRRNKMNNILRVISNYQQS 360
            ..:.|||..|::...|.:||||::||||.:|:...|:  :.||....:...:::|:|.|..:||:
 Frog  1129 GRFKNLRETLKNCNPPSVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQT 1193

  Fly   361 NYKHLQKHEATQKYLTSIRYIEELQNIFEEDQYKRSLNLEPASPS 405
            .|:...:.:.||..|...|.::      |::.|:.||.:||..|:
 Frog  1194 PYRIEHQPKVTQFLLNKSRILD------EDNLYELSLRIEPRLPA 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539	76/238 (32%)
		PH_RalGPS1_2	578..692	CDD:270120
		PH	578..685	CDD:278594
rasgrf2	XP_002942408.2	PH_RasGRF1_2	19..154	CDD:270081
		RhoGEF	243..424	CDD:214619
		PH	488..582	CDD:365918
		RasGEF_N	634..>682	CDD:366199
		REM	<896..967	CDD:383003	10/80 (13%)
		RasGEF	993..1229	CDD:214539	80/259 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910