Protein Alignment RalGPS and rapgefl1

DIOPT Version :10

• Sequence 1: NP_725613.1
• Gene: RalGPS / 36881
• FlyBaseID: FBgn0034158
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: XP_012826984.1
• Gene: rapgefl1 / 100145761
• XenbaseID: XB-GENE-994178
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 129/312 - (41%)
• Gaps: 52/312 - (16%)

  Fly   124 PDSPGCYYTIAA--------------SAAP-PSKSQSLPAHASIKQLDAVILSALRVPADVLANQ 173
            ||. ||.:|...              |..| |.:.|..|..:.|.          |:.|:.||||
 Frog   341 PDD-GCIFTTLGINSHLFACNREELRSLVPLPEEVQLPPEDSHIH----------RIEAEDLANQ 394

  Fly   174 ITLLDFPVFAQIQPDELSSCAWTKKDKHVNTPNIVAFTKRFNHTSFWTVQEILNAEQPKQRAEII 238
            ::...:.:|:.:...|.....:..:.....|.|:....:|.:....|...:.|..|.|.:|.:::
 Frog   395 LSAFHWELFSCVHELEFIDYVFHVERGRRETANLELLLQRCSEVQHWVSTQTLLCEGPARRTQLL 459

  Fly   239 THFIKVAKKLHELNNLHSLFAIISAMQSASIYRLTKTW----------AC--LSKKDRNAFDRLS 291
            ..|||.|....:..:|.|.|||:..:.:.::.||..||          .|  |..|.:|.|.:..
 Frog   460 KKFIKTAAICKQNQDLLSFFAIVMGLDNGAVSRLRVTWEGTIDRARNARCQKLPGKCKNLFRKFE 524

  Fly   292 DIFSDQDNWANLRSYLESLRLPCIPYLGLFLTDLIYIDLAHPHKG------GLEPEQRRNKMNNI 350
            ::.....|..:.|..:..:|.|.||::.|.|.||.::     |:|      ||...::.:.:...
 Frog   525 NLTDPCRNHKSYREMVSRMRPPVIPFIPLILKDLTFL-----HEGSKTFIDGLVNVEKMHAIAEK 584

  Fly   351 LRVISNYQQSNYKHLQKHEATQKYLTSIRYIEELQNIFEED-QYKRSLNLEP 401
            :|.:..| :||...|.. :.:..:|.:..|:.:.|.|..:: .::.|..|||
 Frog   585 VRTVRKY-RSNQLRLDT-DVSPTHLQNKAYVRQFQVIDNQNLLFELSCKLEP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RalGPS	NP_725613.1	RasGEF	169..335	CDD:459872	42/177 (24%)
		PH_RalGPS1_2	578..692	CDD:270120
rapgefl1	XP_012826984.1	REM	108..209	CDD:470601
		RasGEF	383..634	CDD:214539	60/267 (22%)