DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5522 and rapgef4b

DIOPT Version :9

Sequence 1:	NP_725613.1	Gene:	CG5522 / 36881	FlyBaseID:	FBgn0034158	Length:	702	Species:	Drosophila melanogaster
Sequence 2:	NP_001108368.1	Gene:	rapgef4b / 100141331	ZFINID:	ZDB-GENE-080219-4	Length:	427	Species:	Danio rerio

Alignment Length:	137	Identity:	25/137 - (18%)
Similarity:	44/137 - (32%)	Gaps:	46/137 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   547 ADLTSLESAEGIMC------DFTGSDCDLMSPEAAAAMHGCVRRKTVQKEGRKPAVASWQRY--- 602
            |...|:.|||.|:|      :.:|.|.|::.                   .|...|.:::::
Zfish     6 ASAHSVASAEWIICLDKRPAERSGEDVDIIL-------------------ARLKGVKAFEKFHPN 51

  Fly   603 -WLQIWANSLVYFPPKSFKGSERNDFKREPCKVCPLDGWYA--------HVSDNTKHKNTFELCH 658
             ..||.......:..|......:.|..         ..|||        .||:...|::...:|.
Zfish    52 LLQQICMCGFYEYLEKGITLYRQGDIG---------TSWYAVLSGSLDVKVSETANHQDAVTICT 107

  Fly   659 RTLGTVY 665
            ..:||.:
Zfish   108 LGVGTAF 114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5522	NP_725613.1	RasGEF	163..400	CDD:214539
		PH_RalGPS1_2	578..692	CDD:270120	15/100 (15%)
		PH	578..685	CDD:278594	15/100 (15%)
rapgef4b	NP_001108368.1	CAP_ED	44..153	CDD:237999	13/80 (16%)
		Crp	65..>153	CDD:223736	11/59 (19%)
		DEP_Epac	204..332	CDD:239884
		CAP_ED	356..>406	CDD:237999
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910