Protein Alignment Arp53D and ACTL6A

DIOPT Version :9

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 430
• Identity: 146/430 - (33%)
• Similarity: 225/430 - (52%)
• Gaps: 57/430 - (13%)

  Fly    36 MSSEVDSNSHHAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGR--PRHLNVLLDSVIGDS----- 93
            ||..|.......|:|.|.||...:||::.||.|:..||:.:|.  .|.....|..:.||.
Human     1 MSGGVYGGDEVGALVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGG 65

  Fly    94 ---VIGEAAAR-KRGILTLKYPIEHGMVKNWDEMEMVWQHTYEL-LRADPMDLPALLTEAPLNPK 153
               .|...|.| .|..:....|:::|||::||..:.:..|||:: ::::....|.|::|||.|.:
Human    66 PTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLMSEAPWNTR 130

  Fly   154 KNREKMTEIMFEHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHT--VPIYEGFALPHACV 216
            ..|||:||:||||:.:|||::...|||:.:|.||:.|:::||  |.|||  :|:::|:.|....|
Human   131 AKREKLTELMFEHYNIPAFFLCKTAVLTAFANGRSTGLILDS--GATHTTAIPVHDGYVLQQGIV 193

  Fly   217 RVDLAGRDLTDYLCKLLLERGVTMGTS---AEREIVRE-------IKEKLCYVSMNYAKEM---- 267
            :..|||..:|....:|..|..:.:...   |.:|.|||       .||||..|:.::...|
Human   194 KSPLAGDFITMQCRELFQEMNIELVPPYMIASKEAVREGSPANWKRKEKLPQVTRSWHNYMCNCV 258

  Fly   268 --DLHGKV------------------ETYELPDGQKIVLGCERFRCPEALFQPS----LLGQEVM 308
              |....|                  ..||.|:|.....|.||.:.||.||.||    |.|..::
Human   259 IQDFQASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVKGLSGNTML 323

  Fly   309 GIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKV---NASPD 370
            |:......|:..||:|:|..:|.:::::||.|:.::...|..::|::..|||:|:|:   |.:.:
Human   324 GVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKLIANNTTVE 388

  Fly   371 RRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKC 410
            ||||.|.|||:||||.:||.|||...||||.|...|.|||
Human   389 RRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERKC 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	143/420 (34%)
		NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	143/419 (34%)
ACTL6A	NP_004292.1	Actin	11..429	CDD:394979	143/420 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920