Protein Alignment Arp53D and ARP8

DIOPT Version :9

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_014784.1
• Gene: ARP8 / 854309
• SGDID: S000005667
• Length: 881
• Species: Saccharomyces cerevisiae
• Alignment Length: 674
• Identity: 110/674 - (16%)
• Similarity: 184/674 - (27%)
• Gaps: 289/674 - (42%)

  Fly     2 STFQIPSRIKIDITNKRAQNILHKYLHLPTSPGNMSSEVDSNSHHAAVVIDNGSGVCKAGFSPED 66
            :|.||.|....|:.:      |....|...|...::.|:|.|...|.:||..||...|.||..:|
Yeast   228 NTSQISSTNTPDVID------LKSLPHSEASAAPLNDEIDLNDPTATIVIHPGSNSIKIGFPKDD 286

  Fly    67 TPRAVFPSIVGRPR---------HL-NVLL----------------------------------- 86
            .| .|.|:.|..|:         |: ||.|
Yeast   287 HP-VVVPNCVAVPKKWLDLENSEHVENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAH 350

  Fly    87 ------------------------DSVIGDSVI--GEAAAR------------KRGILTLKYPIE 113
                                    :.:..||.:  |..|.|            :.|...:|.|..
Yeast   351 EQVVSFNENSKPEIISEKNDPSPIEWIFDDSKLYYGSDALRCVDEKFVIRKPFRGGSFNVKSPYY 415

  Fly   114 HGMVKNWDEMEMVWQHTY--ELLRADPM---DLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFY 173
            ..:.:...::..:.:|..  |.|...|.   ....:|....:..|.:.|....::....|..|..
Yeast   416 KSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIFKKSHVETFIRVLLTELQFQAVA 480

  Fly   174 VAVQAVLSLYATG-RTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERG 237
            :..:::.:.|..| .|...||:.|...|....:.||..|.|:.:.:|..|.|:|......||:..
Yeast   481 IIQESLATCYGAGISTSTCVVNIGAAETRIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSD 545

  Fly   238 VTM---------------------GTSAEREIVREIKEKLCYVSMNYAKEMDLHGKVETYELPDG 281
            ..:                     .|..:.::..::     |..||.:...    ..|.||....
Yeast   546 FPLQDWKIDSKHGWLLAERLKKNFTTFQDADVAVQL-----YNFMNRSPNQ----PTEKYEFKLF 601

  Fly   282 QKIVLGCERFRCPEALFQPSL-------------------------------------------- 302
            .:::|      .|.|||.|.:
Yeast   602 DEVML------APLALFFPQIFKLIRTSSHKNSSLEFQLPESRDLFTNELNDWNSLSQFESKEGN 660

  Fly   303 -----------------------------------LGQEVMGIHEATHHSITN----CDMDLRKD 328
                                               |.:....:.:|...||.|    .|:.....
Yeast   661 LYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNTLKENFAPLEKAIVQSIANASITADVTRMNS 725

  Fly   329 MYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSI---------------RIK------VNASPDR- 371
            .|:||::.||::....::. .|.|...:..||:               .||      ||| ||:
Yeast   726 FYSNILIVGGSSKIPALDF-ILTDRINIWRPSLLSSASFPQFYKKLTKEIKDLEGHYVNA-PDKT 788

  Fly   372 --------------------------------------------------RFSVWTGGSVLASLT 386
                                                              ...:|.|.||||.:.
Yeast   789 EDENKQILQAQIKEKIVEELEEQHQNIEHQNGNEHIFPVSIIPPPRDMNPALIIWKGASVLAQIK 853

  Fly   387 SFQNMWIDSLEYEEVGSAIVHRKC 410
            ..:.::|.:.:::..||.|:..||
Yeast   854 LVEELFITNSDWDVHGSRILQYKC 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	99/630 (16%)
		NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	99/629 (16%)
ARP8	NP_014784.1	NBD_sugar-kinase_HSP70_actin	42..>447	CDD:418402	41/225 (18%)
		ACTIN	266..878	CDD:214592	99/630 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3387
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860