DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp53D and Actrt3

DIOPT Version :9

Sequence 1:	NP_477037.2	Gene:	Arp53D / 36879	FlyBaseID:	FBgn0011743	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_083966.1	Gene:	Actrt3 / 76652	MGIID:	1923902	Length:	369	Species:	Mus musculus

Alignment Length:	376	Identity:	162/376 - (43%)
Similarity:	246/376 - (65%)	Gaps:	15/376 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 NSHHAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPR-HLNVLLDSVIGDS----VIGEAAARK 102
            :.:...||||||||:.|||.:....|:.|:|:|:||.: |        ..||    .:|:.|..:
Mouse     2 SGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRSKGH--------TADSRQELCVGDQAQER 58

  Fly   103 RGILTLKYPIEHGMVKNWDEMEMVWQHTYEL-LRADPMDLPALLTEAPLNPKKNREKMTEIMFEH 166
            |..|::.||:|.|::.:|.:||::|:|.|:. |..:..|.|.|:||..|||..:|:.::|:.||:
Mouse    59 RSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFEN 123

  Fly   167 FQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCK 231
            ..|||||::.||||:|:|.|.|.|:|::||.|:|..|||:||:.|.|...::::||.|||.||..
Mouse   124 LGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMM 188

  Fly   232 LLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHGKVE-TYELPDGQKIVLGCERFRCPE 295
            ||...|:.:..:.:|::|.:|||..|||:|||..||.....:| .|.||||:.:.|..:.|.|||
Mouse   189 LLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTKDSNLEKIYTLPDGKTVKLHKQLFHCPE 253

  Fly   296 ALFQPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPS 360
            |||.|.|:..:..||.:....||..||.|||...::||:||||:|.|..::.|.::|:.::||.:
Mouse   254 ALFSPYLVNVDAPGIDKMCFGSIMKCDTDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPAN 318

  Fly   361 IRIKVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            ..::|.|.|:|:.|||.|||:||||::||:|||.:.|:||||..|||::||
Mouse   319 TAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	160/371 (43%)
Arp53D	NP_477037.2	NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	160/370 (43%)
Actrt3	NP_083966.1	ACTIN	5..369	CDD:214592	160/371 (43%)
Actrt3	NP_083966.1	NBD_sugar-kinase_HSP70_actin	9..369	CDD:302596	159/367 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11937
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110