Protein Alignment Arp53D and ACTG2

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001606.1
• Gene: ACTG2 / 72
• HGNCID: 145
• Length: 376
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 236/369 - (63%)
• Similarity: 291/369 - (78%)
• Gaps: 5/369 - (1%)

  Fly    48 AVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYPI 112
            |:|.|||||:|||||:.:|.||||||||||||||..|::.....||.:|:.|..|||||||||||
Human     8 ALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPI 72

  Fly   113 EHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAV 176
            |||::.|||:||.:|.|: |..||..|.:.|.||||||||||.||||||:||||.|.|||.|||:
Human    73 EHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAI 137

  Fly   177 QAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMG 241
            ||||||||:|||.|||:||||||||.||||||:|||||.:|:|||||||||||.|:|.|||.:..
Human   138 QAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFV 202

  Fly   242 TSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCERFRCPEALFQPSL 302
            |:|||||||:||||||||::::..||    ......::|||||||.|.:|.|||||||.|||||.
Human   203 TTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSF 267

  Fly   303 LGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNA 367
            :|.|..||||.|::||..||:|:|||:|||.||||||||:..|..|..:::|.:||.:::||:.|
Human   268 IGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIA 332

  Fly   368 SPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            .|:|::|||.|||:||||::||.|||...||:|.|.:|||||||
Human   333 PPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	229/362 (63%)
ACTG2	NP_001606.1	ASKHA_NBD_actin	7..371	CDD:466823	229/362 (63%)