Protein Alignment Arp53D and ACTB

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001092.1
• Gene: ACTB / 60
• HGNCID: 132
• Length: 375
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 241/370 - (65%)
• Similarity: 294/370 - (79%)
• Gaps: 5/370 - (1%)

  Fly    47 AAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYP 111
            ||:|:|||||:|||||:.:|.||||||||||||||..|::.....||.:|:.|..||||||||||
Human     6 AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYP 70

  Fly   112 IEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVA 175
            ||||:|.|||:||.:|.|| |..||..|.:.|.||||||||||.||||||:||||.|..||.|||
Human    71 IEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVA 135

  Fly   176 VQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTM 240
            :||||||||:|||.|||:|||||||||||||||:|||||.:|:|||||||||||.|:|.|||.:.
Human   136 IQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSF 200

  Fly   241 GTSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCERFRCPEALFQPS 301
            .|:|||||||:||||||||::::.:||    ......::|||||||.|.:|.|||||||||||||
Human   201 TTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPS 265

  Fly   302 LLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVN 366
            .||.|..||||.|.:||..||:|:|||:|||.||||||||:..|..|..:::|.:||.:::||:.
Human   266 FLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKII 330

  Fly   367 ASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            |.|:|::|||.|||:||||::||.|||...||:|.|.:|||||||
Human   331 APPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	234/363 (64%)
ACTB	NP_001092.1	ASKHA_NBD_actin	6..370	CDD:466823	234/363 (64%)