DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp53D and si:ch211-241j12.3

DIOPT Version :9

Sequence 1:	NP_477037.2	Gene:	Arp53D / 36879	FlyBaseID:	FBgn0011743	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_017207998.2	Gene:	si:ch211-241j12.3 / 566552	ZFINID:	ZDB-GENE-040724-72	Length:	1245	Species:	Danio rerio

Alignment Length:	365	Identity:	191/365 - (52%)
Similarity:	257/365 - (70%)	Gaps:	2/365 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYPIE 113
            :|:|:|||:.||||:.:|.|.||||:::|||::..|:...|..:..:|..|...||:|||:|||.
Zfish   881 IVLDSGSGLMKAGFADQDLPAAVFPTVIGRPKYEEVMNSCVDRELYVGHDAQHMRGVLTLRYPIR 945

  Fly   114 HGMVKNWDEMEMVWQHTYELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAVQA 178
            ||:|.|||||||:|.|.::||.|.|.|.|.|||||.|||.:||::|.|:|||.|.||..:|||||
Zfish   946 HGVVSNWDEMEMLWTHAFQLLSAAPEDHPVLLTEAALNPLQNRQRMVELMFEAFSVPLTFVAVQA 1010

  Fly   179 VLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMGTS 243
            ||:|||:|||.|:|:||||||:|:||::||:.||||..|:||||.|:|..|.|||||.||.:.||
Zfish  1011 VLALYASGRTTGVVLDSGDGVSHSVPVFEGYCLPHAVQRLDLAGADVTLQLQKLLLESGVCLRTS 1075

  Fly   244 AEREIVREIKEKLCYVSMNYAKEMDLHGKVETYELPDGQKIVLGCERFRCPEALFQPSLLGQEVM 308
            ||.|||||:||:.|:||::|..||........|.||||..:.|..:|||.||.||:|.|:|::..
Zfish  1076 AELEIVREMKERCCFVSVDYEAEMKSSESEIQYTLPDGHTVPLASQRFRAPEILFRPELIGRDHY 1140

  Fly   309 GIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIR--IKVNASPDR 371
            |:||:...||...|:|||:....||:||||.|:...:..|...::..|.|..:.  ::|::.|||
Zfish  1141 GLHESVFRSILQSDLDLRRSFVGNILLSGGNTLLSGLAERLQLEVRAMVPLDLSACVRVSSPPDR 1205

  Fly   372 RFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            .||||:||:.||||...|:.||.:.||||.|..||.||||
Zfish  1206 DFSVWSGGAALASLPEQQSAWISAAEYEEFGPQIVFRKCF 1245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	189/363 (52%)
Arp53D	NP_477037.2	NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	189/363 (52%)
si:ch211-241j12.3	XP_017207998.2	Neuromodulin_N	<411..625	CDD:331332
si:ch211-241j12.3	XP_017207998.2	ACTIN	878..1245	CDD:214592	189/363 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11937
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020