Protein Alignment Arp53D and ACTBL2

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001017992.1
• Gene: ACTBL2 / 345651
• HGNCID: 17780
• Length: 376
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 231/370 - (62%)
• Similarity: 287/370 - (77%)
• Gaps: 5/370 - (1%)

  Fly    47 AAVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYP 111
            :|:|:|||||:|||||..:|.|||||||::|||||..|::.....|..:|:.|..|||:||||||
Human     7 SALVVDNGSGMCKAGFGGDDAPRAVFPSMIGRPRHQGVMVGMGQKDCYVGDEAQSKRGVLTLKYP 71

  Fly   112 IEHGMVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVA 175
            ||||:|.|||:||.:|.|| |..||..|.:.|.||||||||||.||||||:||||.|..||.|||
Human    72 IEHGVVTNWDDMEKIWYHTFYNELRVAPDEHPILLTEAPLNPKINREKMTQIMFEAFNTPAMYVA 136

  Fly   176 VQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTM 240
            :||||||||:|||.|||:||||||||.||||||:|||||.:|:|||||||||||.|:|.|||...
Human   137 IQAVLSLYASGRTTGIVMDSGDGVTHIVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYNF 201

  Fly   241 GTSAEREIVREIKEKLCYVSMNYAKEM----DLHGKVETYELPDGQKIVLGCERFRCPEALFQPS 301
            .|:|||||||::|||||||::::.:||    .......:|||||||.|.:|.||||||||:||||
Human   202 TTTAEREIVRDVKEKLCYVALDFEQEMVRAAASSSPERSYELPDGQVITIGNERFRCPEAIFQPS 266

  Fly   302 LLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVN 366
            .||.|..||||.|.:||..||:|:|||:|||.|||||:||:..|..|..:::..:||.:::||:.
Human   267 FLGIESSGIHETTFNSIMKCDVDIRKDLYANTVLSGGSTMYPGIADRMQKEIITLAPSTMKIKII 331

  Fly   367 ASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            |.|:|::|||.|||:||||::||.|||...||:|.|..|||||||
Human   332 APPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPPIVHRKCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	224/363 (62%)
ACTBL2	NP_001017992.1	ASKHA_NBD_actin	7..371	CDD:466823	224/363 (62%)