DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arp53D and Actr2

DIOPT Version :9

Sequence 1:	NP_477037.2	Gene:	Arp53D / 36879	FlyBaseID:	FBgn0011743	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_017454617.1	Gene:	Actr2 / 289820	RGDID:	1310826	Length:	399	Species:	Rattus norvegicus

Alignment Length:	390	Identity:	167/390 - (42%)
Similarity:	239/390 - (61%)	Gaps:	35/390 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSV--IG----------DSVIGEAAAR 101
            ||.|||:|..|.|::..:.|..:||::||||     ::.|.  :|          |.::|:.|:.
  Rat     9 VVCDNGTGFVKCGYAGSNFPEHIFPALVGRP-----IIRSTTKVGNIEIKNNKKMDLMVGDEASE 68

  Fly   102 KRGILTLKYPIEHGMVKNWDEMEMVWQHTY--ELLRADPMDLPALLTEAPLNPKKNREKMTEIMF 164
            .|.:|.:.||:|:|:|:|||:|:.:|.:|:  |.|..|......||||.|:||.|||||:.|:||
  Rat    69 LRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRSCKILLTEPPMNPTKNREKIVEVMF 133

  Fly   165 EHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYL 229
            |.:|....|||:||||:|||.|...|:||||||||||..|:||||:|||...|:|:||||:|.||
  Rat   134 ETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYL 198

  Fly   230 CKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHGK----VETYELPDGQKIVLGCER 290
            .||||.||.....||:.|.||.||||||||..|..:|..|..:    ||:|.||||:.|.:|.||
  Rat   199 IKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGER 263

  Fly   291 FRCPEALFQPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTE 355
            |..|||||||.|:..|.:|:.|...::|...|:|.|.:.|.:||||||:||:..:..|..::|.:
  Rat   264 FEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQ 328

  Fly   356 MAPPSI-----------RIKVNASPDRRFSVWTGGSVLASLTSFQ-NMWIDSLEYEEVGSAIVHR 408
            :....:           :|::...|.|:..|:.||:|||.:...: |.|:...||:|.|..::.:
  Rat   329 LYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 393

Fly 409 408
Rat 394 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	167/390 (43%)
Arp53D	NP_477037.2	NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	167/390 (43%)
Actr2	XP_017454617.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920