Protein Alignment Arp53D and ACTL9

DIOPT Version :9

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_848620.3
• Gene: ACTL9 / 284382
• HGNCID: 28494
• Length: 416
• Species: Homo sapiens
• Alignment Length: 403
• Identity: 161/403 - (39%)
• Similarity: 239/403 - (59%)
• Gaps: 25/403 - (6%)

  Fly    21 NILHKYLHLPTSPGNMSSEVDSNSHHAAVVIDNGSGVCKAGFSPEDTPRAVFPSIVG-RPRHLNV 84
            |:::|.|. ..|||.::..:...:  .|||||.|:|.||.||:.:.:|.....:|:| :|:.
Human    27 NVVNKPLQ-RDSPGMVADRLPPKT--GAVVIDMGTGTCKVGFAGQASPTYTVATILGCQPKK--- 85

  Fly    85 LLDSVIGDS----VIGEAAARKRGILTLKYPIEHGMVKNWDEMEMVWQHTYEL-LRADPMDLPAL 144
              .:..|.|    .||| |||....|||..|:..|:|.:||..|::|:|..|. ||....|.|.|
Human    86 --PATSGQSGLQTFIGE-AARVLPELTLVQPLRSGIVVDWDAAELIWRHLLEHDLRVATHDHPLL 147

  Fly   145 LTEAPLNPKKNREKMTEIMFEHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGF 209
            .::.|.:|..||||:.|:.||..:.||.|||.|:|||:||.||..|:|||:|.|||:|||:::|:
Human   148 FSDPPFSPATNREKLVEVAFESLRSPAMYVASQSVLSVYAHGRVSGLVVDTGHGVTYTVPVFQGY 212

  Fly   210 ALPHACVRVDLAGRDLTDYLCKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHGKVE 274
            .|.||..|:||||.:||.:|.::||:.|:.:| ..:.::|..||...|||:.::.||   ..:.|
Human   213 NLLHATERLDLAGNNLTAFLAEMLLQAGLPLG-QQDLDLVENIKHHYCYVASDFQKE---QARPE 273

  Fly   275 -----TYELPDGQKIVLGCERFRCPEALFQ-PSLLGQEVMGIHEATHHSITNCDMDLRKDMYANI 333
                 |.:||||:.:.||.|.|:|||.||. |.:.|...:|:......|:....:::|.|:..|:
Human   274 QEYKRTLKLPDGRTVTLGKELFQCPELLFNPPEVPGLSPVGLSTMAKQSLRKLSLEMRADLAQNV 338

  Fly   334 VLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEY 398
            :|.||:::|...|.||..:|....|....:.|.|.|.|.||||.|||:||||.:||:.|:...:|
Human   339 LLCGGSSLFTGFEGRFRAELLRALPAETHVVVAAQPTRNFSVWIGGSILASLRAFQSCWVLREQY 403

  Fly   399 EEVGSAIVHRKCF 411
            ||.|..||:|||:
Human   404 EEQGPYIVYRKCY 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	154/376 (41%)
		NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	154/375 (41%)
ACTL9	NP_848620.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		2/6 (33%)
		NBD_sugar-kinase_HSP70_actin	49..416	CDD:302596	154/378 (41%)
		ACTIN	49..415	CDD:214592	153/377 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11937
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.020