Protein Alignment Arp53D and ACTRT1

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_612146.1
• Gene: ACTRT1 / 139741
• HGNCID: 24027
• Length: 376
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 166/373 - (44%)
• Similarity: 236/373 - (63%)
• Gaps: 8/373 - (2%)

  Fly    46 HA----AVVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGIL 106
            ||    ||:.|||||:||||.|.|..||.|..|::|..: .||.|..:.....:|:.|..|...|
Human     5 HALDVPAVIFDNGSGLCKAGLSGEIGPRHVISSVLGHCK-FNVPLARLNQKYFVGQEALYKYEAL 68

  Fly   107 TLKYPIEHGMVKNWDEMEMVWQHTYEL-LRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVP 170
            .|.||||.|:|..||:||.:|:|.:|. |...|...|.|:||..|||::.|||:.|:|||.|.||
Human    69 HLHYPIERGLVTGWDDMEKLWKHLFERELGVKPSQQPVLMTEPSLNPREIREKLAEMMFETFSVP 133

  Fly   171 AFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLE 235
            .||::..||.:|||:....|:|||||||||.||||:||::||||..::.:||||:|::|.:||..
Human   134 GFYLSNHAVAALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVTKLCMAGRDITEHLTRLLFA 198

  Fly   236 RGVTMGTSAEREIVREIKEKLCYVSMNYAKEM-DLHGKV-ETYELPDGQKIVLGCERFRCPEALF 298
            .|........:.:|..|||||||:::...||: ...|:| ..|.||||..|..|.|.::.||.||
Human   199 SGFNFPCILNKAVVNNIKEKLCYIALEPEKELRKSRGEVLGAYRLPDGHVIHFGDELYQVPEVLF 263

  Fly   299 QPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRI 363
            .|..||....|:.:....||..||.|::..:||:||||||||:...:|.|.::::.::|.....|
Human   264 APDQLGIHSPGLSKMVSSSIMKCDTDIQNKLYADIVLSGGTTLLPGLEERLMKEVEQLASKGTPI 328

  Fly   364 KVNASPDRRFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            |:.|||||.||.|.|.|::.|::||:.||:.|.:::|.|:::|.|:||
Human   329 KITASPDRCFSAWIGASIMTSMSSFKQMWVTSADFKEYGTSVVQRRCF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	161/365 (44%)
ACTRT1	NP_612146.1	ASKHA_NBD_actin_Arp-T1-3	10..367	CDD:466848	159/357 (45%)