DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arp53D and LOC102552318

DIOPT Version :9

Sequence 1:	NP_477037.2	Gene:	Arp53D / 36879	FlyBaseID:	FBgn0011743	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	XP_038957224.1	Gene:	LOC102552318 / 102552318	RGDID:	7506405	Length:	383	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	147/365 - (40%)
Similarity:	212/365 - (58%)	Gaps:	23/365 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 PRAVFPSIVGRPRHLNVLLDSVIGDSV-----------------IGEAAARKRGILTLKYPIEHG 115
            |.|.||  ||....|....||.:.||:                 ||......|..|.:.|||..|
  Rat    21 PLARFP--VGLAPALGSRSDSYVQDSLLPFLQTLLERLEEEDWFIGAEVQNNRPKLNIHYPIFRG 83

  Fly   116 MVKNWDEMEMVWQHT-YELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAVQAV 179
            .:.|||.::.||.:: |..||..|...|.|:|:.||..|:.|.|||:|:||.|..||.|:|.|.|
  Rat    84 AITNWDNVQKVWHYSFYHYLRIAPEQHPILVTDPPLTTKEARSKMTQILFETFNFPALYLANQGV 148

  Fly   180 LSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMGTSA 244
            |||||:|||.|..::||||:|:.|||..|:.|..:..:||.||:|||.||.|||.:.|..:.|:|
  Rat   149 LSLYASGRTSGTTIESGDGMTYFVPIANGYPLHLSTTKVDTAGQDLTVYLMKLLSDNGNMLETTA 213

  Fly   245 EREIVREIKEKLCYVSMNYAKEMDLHGK---VETYELPDGQKIVLGCERFRCPEALFQPSLLGQE 306
            :.|.||::|||.|||:::|..||....:   ::.:.||||::|.||.|.|.|||.||.|||:|:.
  Rat   214 DLEHVRDLKEKCCYVALDYDMEMSKTSESSFLKKFTLPDGKEISLGQETFMCPEVLFNPSLVGKN 278

  Fly   307 VMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNASPDR 371
            ..||......|||:||....::::..|:|||||.....:..|..:::.::..|.:.:||..||..
  Rat   279 YPGIDMQAQQSITSCDKSHWRNLFGYIILSGGTGTCSGLRFRLQREIAKLVSPELSVKVVTSPYA 343

  Fly   372 RFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            ::..|.|.|:|.||..|::|||.:.||.|:|.:::.|:.|
  Rat   344 KYGAWVGASILCSLPMFKDMWITNHEYLEIGPSVICRRTF 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ACTIN	46..411	CDD:214592	146/363 (40%)
Arp53D	NP_477037.2	NBD_sugar-kinase_HSP70_actin	47..411	CDD:302596	146/363 (40%)
LOC102552318	XP_038957224.1	NBD_sugar-kinase_HSP70_actin	57..383	CDD:418402	135/325 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D649708at2759
OrthoFinder	1	1.000	-	-		FOG0000057
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920