Protein Alignment Arp53D and ACTR1B

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_005726.1
• Gene: ACTR1B / 10120
• HGNCID: 168
• Length: 376
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 195/365 - (53%)
• Similarity: 263/365 - (72%)
• Gaps: 2/365 - (0%)

  Fly    49 VVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSVIGDSVIGEAAARKRGILTLKYPIE 113
            |||||||||.||||:.:..|:..||:.||||:|:.|:..::.||..||..|...||:||::||:|
Human    12 VVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGPKAEEHRGLLTIRYPME 76

  Fly   114 HGMVKNWDEMEMVWQHTY--ELLRADPMDLPALLTEAPLNPKKNREKMTEIMFEHFQVPAFYVAV 176
            ||:|::|::||.:||:.|  :.|:....:.|.|||||||||.|||||..|:.||.|.|||.::::
Human    77 HGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKNREKAAEVFFETFNVPALFISM 141

  Fly   177 QAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYLCKLLLERGVTMG 241
            ||||||||||||.|:|:||||||||.||||||||:||:.:|||:||||::.||..||.:.||...
Human   142 QAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVSRYLRLLLRKEGVDFH 206

  Fly   242 TSAEREIVREIKEKLCYVSMNYAKEMDLHGKVETYELPDGQKIVLGCERFRCPEALFQPSLLGQE 306
            ||||.|:||.|||:.||:|:|..|:..|..:...|.||||..:.:|..|||.||.||||.|:|.|
Human   207 TSAEFEVVRTIKERACYLSINPQKDEALETEKVQYTLPDGSTLDVGPARFRAPELLFQPDLVGDE 271

  Fly   307 VMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTEMAPPSIRIKVNASPDR 371
            ..|:||....:|...|||||:.::||||||||:|:|:....|.|.::.::||..|:||::|..:|
Human   272 SEGLHEVVAFAIHKSDMDLRRTLFANIVLSGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQER 336

  Fly   372 RFSVWTGGSVLASLTSFQNMWIDSLEYEEVGSAIVHRKCF 411
            .:|.|.|||:||||.:|:.||:...||||.||..:|||.|
Human   337 LYSTWIGGSILASLDTFKKMWVSKKEYEEDGSRAIHRKTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	191/358 (53%)
ACTR1B	NP_005726.1	ASKHA_NBD_Arp1	9..375	CDD:466820	193/362 (53%)