Protein Alignment Arp53D and ACTR2

DIOPT Version :10

• Sequence 1: NP_477037.2
• Gene: Arp53D / 36879
• FlyBaseID: FBgn0011743
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001005386.1
• Gene: ACTR2 / 10097
• HGNCID: 169
• Length: 399
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 167/390 - (42%)
• Similarity: 240/390 - (61%)
• Gaps: 35/390 - (8%)

  Fly    49 VVIDNGSGVCKAGFSPEDTPRAVFPSIVGRPRHLNVLLDSV--IG----------DSVIGEAAAR 101
            ||.|||:|..|.|::..:.|..:||::||||     ::.|.  :|          |.::|:.|:.
Human     9 VVCDNGTGFVKCGYAGSNFPEHIFPALVGRP-----IIRSTTKVGNIEIKNNKKMDLMVGDEASE 68

  Fly   102 KRGILTLKYPIEHGMVKNWDEMEMVWQHTY--ELLRADPMDLPALLTEAPLNPKKNREKMTEIMF 164
            .|.:|.:.||:|:|:|:|||:|:.:|.:|:  |.|..|..:...||||.|:||.|||||:.|:||
Human    69 LRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMF 133

  Fly   165 EHFQVPAFYVAVQAVLSLYATGRTVGIVVDSGDGVTHTVPIYEGFALPHACVRVDLAGRDLTDYL 229
            |.:|....|||:||||:|||.|...|:||||||||||..|:||||:|||...|:|:||||:|.||
Human   134 ETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYL 198

  Fly   230 CKLLLERGVTMGTSAEREIVREIKEKLCYVSMNYAKEMDLHGK----VETYELPDGQKIVLGCER 290
            .||||.||.....||:.|.||.||||||||..|..:|..|..:    ||:|.||||:.|.:|.||
Human   199 IKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGER 263

  Fly   291 FRCPEALFQPSLLGQEVMGIHEATHHSITNCDMDLRKDMYANIVLSGGTTMFRNIEHRFLQDLTE 355
            |..|||||||.|:..|.:|:.|...::|...|:|.|.:.|.:||||||:||:..:..|..::|.:
Human   264 FEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQ 328

  Fly   356 MAPPSI-----------RIKVNASPDRRFSVWTGGSVLASLTSFQ-NMWIDSLEYEEVGSAIVHR 408
            :....:           :|::...|.|:..|:.||:|||.:...: |.|:...||:|.|..::.:
Human   329 LYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWMTRQEYQEKGVRVLEK 393

  Fly   409  408
            Human   394  393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp53D	NP_477037.2	ASKHA_ATPase-like	47..406	CDD:483947	167/386 (43%)
ACTR2	NP_001005386.1	ASKHA_NBD_Arp2	7..393	CDD:466821	167/388 (43%)