DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sod2 and SOD2

DIOPT Version :9

Sequence 1:	NP_001286503.1	Gene:	Sod2 / 36878	FlyBaseID:	FBgn0010213	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_011872.1	Gene:	SOD2 / 856399	SGDID:	S000001050	Length:	233	Species:	Saccharomyces cerevisiae

Alignment Length:	220	Identity:	97/220 - (44%)
Similarity:	131/220 - (59%)	Gaps:	16/220 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ISQTASLAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEE-----AK 66
            :|..::.|.|.|.|||.|.:|:.||||.|..:|.|||:.||||||||..|.|.:|.:|     ||
Yeast    16 LSLLSTTARRTKVTLPDLKWDFGALEPYISGQINELHYTKHHQTYVNGFNTAVDQFQELSDLLAK 80

  Fly    67 --SKSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNK----TQPSDDLKKAIESQWKSLEEFKK 125
              |.::..|:|.:...::|:|||..||.:||:||:|..    ..|:..|.|||:.|:.||:|..|
Yeast    81 EPSPANARKMIAIQQNIKFHGGGFTNHCLFWENLAPESQGGGEPPTGALAKAIDEQFGSLDELIK 145

  Fly   126 ELTTLTVAVQGSGWGWLGFN-KKSGKLQLAALPNQDPLEASTG-LIPLFGIDVWEHAYYLQYKNV 188
            ...|....||||||.::..| ...|||.:....|||.:   || |:||..||.|||||||||:|.
Yeast   146 LTNTKLAGVQGSGWAFIVKNLSNGGKLDVVQTYNQDTV---TGPLVPLVAIDAWEHAYYLQYQNK 207

  Fly   189 RPSYVEAIWDIANWDDISCRFQEAK 213
            :..|.:|||::.||.:.|.||...|
Yeast   208 KADYFKAIWNVVNWKEASRRFDAGK 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sod2	NP_001286503.1	SodA	16..214	CDD:223678	95/211 (45%)
		Sod_Fe_N	18..99	CDD:278509	41/87 (47%)
		Sod_Fe_C	105..208	CDD:280872	48/104 (46%)
SOD2	NP_011872.1	SodA	25..233	CDD:223678	95/211 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	91	1.000	Domainoid score	I1761
eggNOG	1	0.900	-	-		E1_COG0605
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H530
Inparanoid	1	1.050	173	1.000	Inparanoid score	I996
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62294
OrthoFinder	1	1.000	-	-		FOG0002017
OrthoInspector	1	1.000	-	-		oto99523
orthoMCL	1	0.900	-	-		OOG6_100280
Panther	1	1.100	-	-	LDO	PTHR11404
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1373
SonicParanoid	1	1.000	-	-		X1932
TreeFam	1	0.960	-	-
	14	13.860