DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sod2 and MSD1

DIOPT Version :9

Sequence 1:	NP_001286503.1	Gene:	Sod2 / 36878	FlyBaseID:	FBgn0010213	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_187703.1	Gene:	MSD1 / 820263	AraportID:	AT3G10920	Length:	231	Species:	Arabidopsis thaliana

Alignment Length:	205	Identity:	107/205 - (52%)
Similarity:	141/205 - (68%)	Gaps:	9/205 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 ISQTAS--LAVRG--KHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKS 67
            :.:|:|  |.:||  ..|||.|||||.||||.|..|||::|||||||.||.|.|.|.|||::|.:
plant    15 LKETSSRLLRIRGIQTFTLPDLPYDYGALEPAISGEIMQIHHQKHHQAYVTNYNNALEQLDQAVN 79

  Fly    68 KSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNK----TQPSDDLKKAIESQWKSLEEFKKELT 128
            |.|.:.:::|..|::||||||:||:|||:||:|:.    ..|...|..||::.:.|||...|:::
plant    80 KGDASTVVKLQSAIKFNGGGHVNHSIFWKNLAPSSEGGGEPPKGSLGSAIDAHFGSLEGLVKKMS 144

  Fly   129 TLTVAVQGSGWGWLGFNKKSGKLQLAALPNQDPLEASTG-LIPLFGIDVWEHAYYLQYKNVRPSY 192
            ....|||||||.|||.:|:..||.:....|||||....| |:||.||||||||||||||||||.|
plant   145 AEGAAVQGSGWVWLGLDKELKKLVVDTTANQDPLVTKGGSLVPLVGIDVWEHAYYLQYKNVRPEY 209

  Fly   193 VEAIWDIANW 202
            ::.:|.:.||
plant   210 LKNVWKVINW 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sod2	NP_001286503.1	SodA	16..214	CDD:223678	104/194 (54%)
		Sod_Fe_N	18..99	CDD:278509	48/80 (60%)
		Sod_Fe_C	105..208	CDD:280872	52/99 (53%)
MSD1	NP_187703.1	PLN02471	1..231	CDD:215262	107/205 (52%)
		Sod_Fe_N	30..111	CDD:278509	48/80 (60%)
		Sod_Fe_C	121..224	CDD:280872	52/99 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E1_COG0605
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H530
Inparanoid	1	1.050	218	1.000	Inparanoid score	I1215
OMA	1	1.010	-	-		QHG62294
OrthoDB	1	1.010	-	-		D1353361at2759
OrthoFinder	1	1.000	-	-		FOG0002017
OrthoInspector	1	1.000	-	-		otm3329
orthoMCL	1	0.900	-	-		OOG6_100280
Panther	1	1.100	-	-	LDO	PTHR11404
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1932
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840