DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sod2 and SOD2

DIOPT Version :9

Sequence 1:	NP_001286503.1	Gene:	Sod2 / 36878	FlyBaseID:	FBgn0010213	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_000627.2	Gene:	SOD2 / 6648	HGNCID:	11180	Length:	222	Species:	Homo sapiens

Alignment Length:	203	Identity:	126/203 - (62%)
Similarity:	157/203 - (77%)	Gaps:	1/203 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LAVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKSKSDTTKLIQL 77
            |..|.||:||.|||||.||||.|..:||:|||.|||..||||||..||:.:||.:|.|.|..|.|
Human    20 LGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIAL 84

  Fly    78 APALRFNGGGHINHTIFWQNLSPN-KTQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGW 141
            .|||:|||||||||:|||.||||| ..:|..:|.:||:..:.|.::||::||..:|.||||||||
Human    85 QPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGW 149

  Fly   142 LGFNKKSGKLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDIS 206
            |||||:.|.||:||.||||||:.:||||||.||||||||||||||||||.|::|||::.||::::
Human   150 LGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVT 214

  Fly   207 CRFQEAKK 214
            .|:...||
Human   215 ERYMACKK 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sod2	NP_001286503.1	SodA	16..214	CDD:223678	123/198 (62%)
		Sod_Fe_N	18..99	CDD:278509	53/80 (66%)
		Sod_Fe_C	105..208	CDD:280872	64/102 (63%)
SOD2	NP_000627.2	SodA	23..222	CDD:223678	123/198 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148075
Domainoid	1	1.000	152	1.000	Domainoid score	I4328
eggNOG	1	0.900	-	-		E1_COG0605
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H530
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2947
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62294
OrthoDB	1	1.010	-	-		D1353361at2759
OrthoFinder	1	1.000	-	-		FOG0002017
OrthoInspector	1	1.000	-	-		oto89750
orthoMCL	1	0.900	-	-		OOG6_100280
Panther	1	1.100	-	-	LDO	PTHR11404
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1932
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770