DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5348 and CAX7

DIOPT Version :9

Sequence 1:	NP_611156.3	Gene:	CG5348 / 36877	FlyBaseID:	FBgn0034156	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_197288.1	Gene:	CAX7 / 831654	AraportID:	AT5G17860	Length:	570	Species:	Arabidopsis thaliana

Alignment Length:	603	Identity:	139/603 - (23%)
Similarity:	243/603 - (40%)	Gaps:	156/603 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 RCEFVQKAEDCNSSTNVIPYMRLLACDLKCINQFQEMIFIALFVAFCFQILVLLIYTINVYYSPA 108
            :|.:::....|... ..|.|:::..|   ...|...:..:.| .|:.|.:..||..|...|:.|:
plant    68 KCSYIRSQSKCGPQ-GYIDYLKIFFC---IFGQSPVLGHLVL-SAWLFVLFYLLGDTAASYFCPS 127

  Fly   109 LKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLASVERHVPVFANN----LSSALFVITISGGLI 169
            |.::|:.|.::..:|||||::.||.:.|.|:::.|..|     :||    |:|.|      || .
plant   128 LDSLSKVLKLSPTMAGVTLLSLGNGAPDLFSSVVSFTR-----SNNGDFGLNSIL------GG-A 180

  Fly   170 FYISPFKM----------------NSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVL 218
            |::|.|.:                ||:  :||::|||:|..            .||        |
plant   181 FFVSSFVVGTICVLIGSRDVAIDRNSF--IRDVVFLLVALC------------CLG--------L 223

  Fly   219 LVYISYIIINVA----DVYLLQKTIASTRTKMQKLLDEKQ--TPEIALKLQDLERKLEYYSQDTR 277
            :::|..:.|.||    .:|||.....|    :....|.|:  :.:|....:||
plant   224 IIFIGKVTIWVALCYLSIYLLYVGFLS----VSHFFDRKKRMSDQILRSREDL------------ 272

  Fly   278 VEILEKSSSISITRIRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQA 342
                   :.:.::.:.|     |...::::..:.|:..|:.:..|..:  .|..|..|
plant   273 -------AEMGVSLLGY-----IAEEKLALPEKTTQEFKIVFEDSPKR--HRSCFSVL------- 316

  Fly   343 WKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRK 407
                      :.:|..|..:...|.||:|..|.    |:|....::..:.|.|...::.|  |..
plant   317 ----------VSIIGLPLYLPRRLTIPVVCEEK----WSKPCAVVSTAIAPVLLTELYCS--HYS 365

  Fly   408 GN----FLWYISLQNTLIYGASSFVLTVPFAVFILFHARTDVPPSYHWVFTIMNLTGSMFLIFLC 468
            |:    .|:.||....||.|..:::.|          .::..|..:..|:.:...|.|:...::.
plant   366 GSQRNLILYIISGSIGLIVGILAYLTT----------EKSHPPKKFSLVWLLGGFTMSVTWTYMI 420

  Fly   469 ATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHG---YPKMAFASAIGGSFFT 530
            |.|:.::|..:|||..|..:.:|.||.|:..:||.|.||..||.||   ..::|.:....|..|.
plant   421 AQELVSLLISLGNIFGISPSVLGLTVLAWGNSLGDLIANVTVAFHGGNDGAQIALSGCYAGPLFN 485

  Fly   531 IVVTGNTVAYVRSLVGNRSEHHMEEYGEIAFI-FLNMALFTI------LLWSTTLGFFARRSMGL 588
            .|:.......:.||.         ||..:..| ..|..|.|:      |||:  |....::.|.|
plant   486 TVIGLGVPLVISSLA---------EYPGVYIIPSDNSLLETLGFLMVGLLWA--LVIMPKKKMRL 539

  Fly   589 YSI---GLYVVYLLFVTL 603
            ..:   ||..:||.|::|
plant   540 DKLVGGGLLAIYLCFLSL 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	34/119 (29%)
CG5348	NP_611156.3	Na_Ca_ex	458..603	CDD:279963	45/157 (29%)
CAX7	NP_197288.1	PLN03151	30..566	CDD:215604	139/603 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840