DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5348 and AT5G17850

DIOPT Version :9

Sequence 1:	NP_611156.3	Gene:	CG5348 / 36877	FlyBaseID:	FBgn0034156	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001318589.1	Gene:	AT5G17850 / 831653	AraportID:	AT5G17850	Length:	559	Species:	Arabidopsis thaliana

Alignment Length:	616	Identity:	132/616 - (21%)
Similarity:	245/616 - (39%)	Gaps:	157/616 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CFAANNF-PFEERCEFVQKAEDCNSSTNVIPYMRLLACDLK---CINQFQEMIFIALFVAFCFQI 93
            |.|..:| .::.:|.:::..:.| :|.....|:..|.|:.:   .:.||  ::|:.|.:.|
plant    46 CSALKHFHDYKSKCAYLKSIDPC-ASQGFFDYLSFLYCNFEGFPILGQF--LLFLWLLLLF---- 103

  Fly    94 LVLLIYTINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLAS-VERHVPVFANNLSS 157
             .||.:|.:.|:..:|:::|:.|:::..:|||||::.||.:.|.||:|.| :......:...|::
plant   104 -YLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLVSFMGESKGTYDVGLNT 167

  Fly   158 AL----FVITISGGLI---FYISPFKMNSYETVRDILFLL-----LATLLMDYFAYTTNHF--AL 208
            .:    ||..:..|:|   .:....::.....:|||.|..     ||.:|:    |...:|  ||
plant   168 VVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILV----YGKINFWGAL 228

  Fly   209 GYEFKFFIVLLVYISYIIINVADVYLLQKTIASTRTKMQKLLDEKQTPEIALKLQDLERKLEYYS 273
            |    |..:..||::::::             |.|....:                        .
plant   229 G----FCSLYAVYVAFVVL-------------SWRFGGDQ------------------------G 252

  Fly   274 QDTRVEILEKSSSISITRIRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGIFRDFFLALRPI 338
            .::.:|.:.|..|:|...::...:..|.:..|:...:...:      ...:|   |.::
plant   253 AESDLESIHKRGSLSEPILQRDGLEEIEDGVVNGEHQIVDD------DDDHQ---RYYY------ 302

  Fly   339 KCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSF 403
                ||:.     |:..|..|..:...|.||:|..:.    |:|.|...:|...|.|.
plant   303 ----WKRL-----VIWAITLPLNLPRILTIPVVSEDK----WSKPLAVASVTFAPVLL------- 347

  Fly   404 MHRKGNFLWYISLQNTLIYGASSFVLTVPFAV---------FILFHARTDVPPSYHWVFT----- 454
                 :|||....:.|      ||...|.:.:         ||.......:.|...|:..
plant   348 -----SFLWNWKRKPT------SFEAGVVYLIGCLIGIALGFIAGATTKKLTPPKKWLLPWLAGG 401

  Fly   455 -IMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHG---Y 515
             :|::|.|    ::.|.|:..:|..:|.|..:..:.:|.||.|:..::|.|..|..:|:|.   .
plant   402 FVMSMTWS----YISAQELVALLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALHDGNEG 462

  Fly   516 PKMAFASAIGGSFF-TIVVTGNTV------AYVRSLVGNRSEHHMEEYGEIAFIFLNMALFTILL 573
            .::|.:....|..| |:...|.::      ||..|:|.......:|..|         .|...|:
plant   463 AQVAVSGCYAGPIFNTLFALGISLVGCAWEAYPLSIVIKTDPRLLESLG---------FLVAGLV 518

  Fly   574 WSTTLGFFAR-RSMGLYSIGLYVVYLLFVTL 603
            ||..:.|..| |..|:..|||.|:||..::|
plant   519 WSFLVLFSNRMRLGGVMGIGLLVIYLASLSL 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	26/107 (24%)
CG5348	NP_611156.3	Na_Ca_ex	458..603	CDD:279963	41/155 (26%)
AT5G17850	NP_001318589.1	PLN03151	34..556	CDD:215604	132/616 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1872
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.940