DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5348 and CAX9

DIOPT Version :9

Sequence 1:	NP_611156.3	Gene:	CG5348 / 36877	FlyBaseID:	FBgn0034156	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_566474.1	Gene:	CAX9 / 820622	AraportID:	AT3G14070	Length:	643	Species:	Arabidopsis thaliana

Alignment Length:	632	Identity:	131/632 - (20%)
Similarity:	235/632 - (37%)	Gaps:	150/632 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 TVSCFAAN-NFPFEERCEFVQKAEDCNSSTNVIPYMRLLACDLKCINQFQEMIFIALFVAFCFQI 93
            ||.|...: :..:.::|||: ||....|......|:....|..:..:....|:.....||    :
plant    89 TVLCSGLHKHMGYADQCEFL-KANPICSPDGFFDYLSFFYCSCRDFSILGYMMLGVWLVA----L 148

  Fly    94 LVLLIYTINVYYSPALKAVSRFLHMNEHLAGVTLMAFGNTSADFFANLAS---VERHVPVFANNL 155
            ..||..|...|:..:|:.:|:.|.:...:|||||:..||.:.|.||::|:   .::......:.|
plant   149 FYLLGNTAADYFCCSLEKLSKLLRLPPTVAGVTLLPLGNGAPDVFASIAAFVGTDKGEVGLNSVL 213

  Fly   156 SSALFVITISGGLIFYI---SPFKMNSYETVRDI---LFLLLATLLMDYFAYTTNHFALGYEFKF 214
            ..|:||.::..|::...   ...|::....:||:   ||.|::.|::......|...|:.:
plant   214 GGAVFVTSVVVGIVSLCVADKEVKIDKNCFIRDLSFFLFSLVSLLVILMVGRVTVRIAIAF---- 274

  Fly   215 FIVLLVYISYIIINVADVYLLQKTIASTRTKMQKLLD-----------------EKQTPEIALKL 262
               :.:|:.|..:..|:|.|.:.   :.|.|::.|..                 ...||.|..:.
plant   275 ---VSIYVVYAFLVAANVILRKH---AKRFKLEALTPLLPMQGSVFSPSVGEDMPMNTPLIETET 333

  Fly   263 QDLERKLEYYSQDTRVEILEKSSSISITRIRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGI 327
            :|...:|:...|                                            :..:.|..|
plant   334 EDGPPRLQSLPQ--------------------------------------------WMWASNVAI 354

  Fly   328 FRDFFLAL------RP----IKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVDYEMEKHGWNK 382
            :.:.|..:      ||    |...|..::....:...|:..|..:...|.||.|    |:..|:|
plant   355 YSNHFAKVSVHDEDRPPWGWIDDTAEVESSSCTKFTSLLEIPLTIPRRLTIPSV----EEDTWSK 415

  Fly   383 LLNAINVVVNPALSISIFLSFMHRKGNFLWY----ISLQNTLIYGASSFVLTVPFAVFILFHART 443
            .....:|.:.|.|..|            ||.    :|||...:....|.|:..........:...
plant   416 TYAVASVSLAPVLLAS------------LWSSQDDVSLQACGVAYFFSVVIGSTLGFLAYKNTEP 468

  Fly   444 DVPPS---YHWVFTIMNLTG---SMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLG 502
            |.||.   ..||     |.|   |:...::.|.|:..:|...|.|..|:.:.:..||.|:..::|
plant   469 DHPPRRFLIPWV-----LGGFIMSIVWFYMIANELVALLVTFGEIYGINPSILALTVLAWGNSMG 528

  Fly   503 TLFANTAVAIHGYP--KMAFASAIGGSFF-TIVVTGNTV---AYVRSLVGNRSEHHMEEYGEIAF 561
            .|.:|.|:.::|..  ::|.:....|..| |:|..|.::   |:.:|............:..:.|
plant   529 DLVSNIALTMNGGDGVQIALSGCYAGPMFNTLVGLGMSMLFGAWSKSPDTYMLPEDKSLFYTLGF 593

  Fly   562 IFLNMALFTILL------WSTTLGFFARRSMGLYSIGLYVVYLLFVT 602
            :.|.:....::|      .|.|||           :||..:||:|||
plant   594 LVLGLVWAMVILPRNDMQPSRTLG-----------VGLIAIYLIFVT 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	27/105 (26%)
CG5348	NP_611156.3	Na_Ca_ex	458..603	CDD:279963	39/160 (24%)
CAX9	NP_566474.1	PLN03151	1..643	CDD:215604	131/632 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41602
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57812
OrthoDB	1	1.010	-	-		D478735at2759
OrthoFinder	1	1.000	-	-		FOG0000933
OrthoInspector	1	1.000	-	-		mtm1105
orthoMCL	1	0.900	-	-		OOG6_101277
Panther	1	1.100	-	-	O	PTHR12266
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X612
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.790