Protein Alignment CG5348 and slc24a3

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_012818629.1
• Gene: slc24a3 / 780317
• XenbaseID: XB-GENE-958238
• Length: 685
• Species: Xenopus tropicalis
• Alignment Length: 629
• Identity: 118/629 - (18%)
• Similarity: 231/629 - (36%)
• Gaps: 170/629 - (27%)

  Fly    69 CDLKCINQFQEMIF---------IALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEHLAG 124
            |....:::|.:.||         :.|.|.|...:...|....:.::.|:|:.:|..|.::|.:||
 Frog   126 CTEPALHEFPDDIFSNEDRRHGAVILHVLFAMYMFYALAIVCDDFFVPSLEKISERLQLSEDVAG 190

  Fly   125 VTLMAFGNTSADFFANLASVERHVPVFANN--------LSSALF----VITISGGLIFYISPFKM 177
            .|.||.|:::.:.|.::      :.||...        :.||:|    :|.:.|  :|......:
 Frog   191 ATFMAAGSSAPELFTSV------IGVFITKGDVGVGTIVGSAVFNILCIIGVCG--LFAGQVVVL 247

  Fly   178 NSYETVRDILFLLLATLLMDYFAYTTNHFALGYEFKFFIVLLVYISYIIINVADVYLLQKTIAST 242
            :::..:||..:..|:.:.:..|.|...   :.: ::..|::::|..||        |:.|..:|.
 Frog   248 SAWCLLRDATYYTLSVIALIVFIYDEK---VSW-WESLILVMMYAVYI--------LIMKYNSSI 300

  Fly   243 RTKMQKLLDEKQTPEIALKLQDLERKLEYYSQDTRVEILEKSSSISITRIRYTTMRMIRNPRVSV 307
            ....::  .:|....:|..|             |....|:.|.....|        |:...:.:.
 Frog   301 HQFFER--RKKSAANLANGL-------------TANSELDDSVHCEAT--------MVLLNKGNC 342

  Fly   308 NRRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVLLLIRAPAVVICTLYIPLVD 372
            ||             |...|..|..|:..|.:. ::.:|.|  |:::....|.....::...::.
 Frog   343 NR-------------KTSVIMVDELLSAYPHQL-SFSEAGL--RIMITSHFPPKTRLSMASRMLI 391

  Fly   373 YEMEKHGWNKLLNAINVVVNPALSISIFLSFMH-------------RKGNFLWYISLQNTLIYGA 424
            .|.:     :|:|: ...||....:||.:...|             |.||     |.:...:..|
 Frog   392 NERQ-----RLINS-RAYVNGESEVSIKIPIKHAVENGTGPGNSTERNGN-----SNRRDDVAEA 445

  Fly   425 SS-------------------------------------------FVLTVPFAVFILFHARTDVP 446
            .:                                           :::|.|..:.:.|.......
 Frog   446 GNETENENEDNENNENDEEEEEEEDDNDGPFTPFEVPSGNADKVKWMVTWPLCLLLYFTVPNCAK 510

  Fly   447 PSYHWVFTIMNLTGSMFLIFLCATEIDTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVA 511
            |.:...|.:..::.||::..|....: .::.:||..|.|.|..||.|..|...::....|:..||
 Frog   511 PRWEKWFMVTFVSSSMWIAALSYVMV-WMVTIIGFTLGIPDVIMGITFLAAGTSVPDCMASLIVA 574

  Fly   512 IHGYPKMAFASAIGGSFFTIVVTGNTVAYVRSLVGNRSEHHMEEYGEIAFIFLN-------MALF 569
            ..|...||.:::||.:.|.|::.......:::|.        .:||  ::|.||       :||.
 Frog   575 RQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLA--------VDYG--SYIQLNSRGLIYSVALL 629

  Fly   570 TILLWSTTLGF-FAR----RSMGLYSIGLYVVYLLFVTLVHEEV 608
            ...|:.|..|. |.:    :.:|:..:.||.|:|....|....|
 Frog   630 LASLFVTVCGVRFNKWRLDKKLGVACLLLYGVFLCLSILTEFNV 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	24/111 (22%)
		Na_Ca_ex	458..603	CDD:279963	39/156 (25%)
slc24a3	XP_012818629.1	2A1904	<129..670	CDD:273344	116/621 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910