Protein Alignment CG5348 and slc24a5

DIOPT Version :9

• Sequence 1: NP_611156.3
• Gene: CG5348 / 36877
• FlyBaseID: FBgn0034156
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001025451.1
• Gene: slc24a5 / 570312
• ZFINID: ZDB-GENE-031210-1
• Length: 513
• Species: Danio rerio
• Alignment Length: 594
• Identity: 109/594 - (18%)
• Similarity: 208/594 - (35%)
• Gaps: 218/594 - (36%)

  Fly    72 KCI----NQFQEMIF---------IALFVAFCFQILVLLIYTINVYYSPALKAVSRFLHMNEHLA 123
            :|:    ::|.|..|         |.::....|.:|:.:....:.|:.|:|:.:|..|.:::.:|
Zfish    57 ECVQPQSSEFPEGFFTVQERKDGGILIYFMIIFYMLLSVSIVCDEYFLPSLEVISERLGLSQDVA 121

  Fly   124 GVTLMAFGNTSADFFANLASVERHVPVFANNLSSALFVITISGGLIFYISPFKMNSYETVRDILF 188
            |.|.||.|:::.:.      |...:.||..  ...:.|.||.|..::              ::|.
Zfish   122 GATFMAAGSSAPEL------VTAFLGVFVT--KGDIGVSTIMGSAVY--------------NLLC 164

  Fly   189 LLLA--------------TLLMDYFAYTTNHFAL--------GYEFKFFIVLLVYISYIIINVAD 231
            :..|              .|..|..||..:..|:        .|.:....:||||..|:.:...|
Zfish   165 ICAACGLLSSAVGRLSCWPLFRDCVAYAISVAAVIAIISDNRVYWYDGACLLLVYGVYVAVLCFD 229

  Fly   232 VYLLQKTIASTRTKMQKLLDEKQTPEI-ALKLQDL----ERKLEYYSQDTRVEILEKSSSISITR 291
            :            ::.:.:.::.:|.. .||.:|.    ::.|..:|.|:.:.:
Zfish   230 L------------RISEYVMQRFSPCCWCLKPRDRDSGEQQPLVGWSDDSSLRV----------- 271

  Fly   292 IRYTTMRMIRNPRVSVNRRYTRNMKLDYTQSKNQGIFRDFFLALRPIKCQAWKQAELLNRVLLLI 356
                             :|.:||         :.|||:|
Zfish   272 -----------------QRRSRN---------DSGIFQD-------------------------- 284

  Fly   357 RAPAVVICTLYIPLVDYEMEKHGWNKLLNAINVVVNPALSISIFLSFMHRKGNFLWYISLQ-NTL 420
                   .:.|..|   .:..||.|::.:...         |:|....|.....||.:||. :||
Zfish   285 -------DSGYSHL---SLSLHGLNEISDEHK---------SVFSMPDHDLKRILWVLSLPVSTL 330

  Fly   421 IYGASSFVLTVP-----------FAVFILFHARTDVPPSYHWV--FTIMNLTGSMFLIFLCATEI 472
            ::      ::||           ...|::         |..|:  ||.:       |:::
Zfish   331 LF------VSVPDCRRPFWKNFYMLTFLM---------SAVWISAFTYV-------LVWM----- 368

  Fly   473 DTVLEVIGNILSIDDNYMGATVKAFTGNLGTLFANTAVAIHGYPKMAFASAIGGSFFTIVVTGNT 537
               :.::|..|.|.|..||.|:.|...::....|:..||..|...||.::.:|.:.|.::..| .
Zfish   369 ---VTIVGETLGIPDTVMGMTLLAAGTSIPDTVASVMVAREGKSDMAMSNIVGSNVFDMLCLG-L 429

  Fly   538 VAYVRSL---VGNRSEHHMEEYGEIAFIFLNMALFTILLWSTTLGFFARRSMGL---YSIGLYVV 596
            ..:::::   ||:     ..|......:|::..    ||.|....|.|....|.   :.:||..:
Zfish   430 PWFIQTVFVDVGS-----PVEVNSSGLVFMSCT----LLLSIIFLFLAVHINGWKLNWKLGLVCL 485

  Fly   597 --YLLFVTL 603
              |:||.||
Zfish   486 ACYILFATL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5348	NP_611156.3	Na_Ca_ex	86..>186	CDD:279963	20/99 (20%)
		Na_Ca_ex	458..603	CDD:279963	33/152 (22%)
slc24a5	NP_001025451.1	ECM27	81..497	CDD:223604	105/570 (18%)
		Na_Ca_ex	84..228	CDD:279963	33/165 (20%)
		Na_Ca_ex	346..497	CDD:279963	40/183 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810